Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50020138
TargetPlatelet-derived growth factor receptor beta(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50626657(CHEMBL5405436)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human PDGFRbeta using MEK1 as substrate incubated for 40 mins by gamma33P-ATP based scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50626657(CHEMBL5405436)
Affinity DataIC50: 19nMAssay Description:Inhibition of human FLT3 using MEK1 as substrate incubated for 40 mins by gamma33P-ATP based scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50626657(CHEMBL5405436)
Affinity DataIC50: 25nMAssay Description:Inhibition of human CSF1R using MEK1 as substrate incubated for 40 mins by gamma33P-ATP based scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50626657(CHEMBL5405436)
Affinity DataIC50: 77nMAssay Description:Inhibition of human c-Kit using MEK1 as substrate incubated for 40 mins by gamma33P-ATP based scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50626657(CHEMBL5405436)
Affinity DataIC50: 100nMAssay Description:Inhibition of human VEGFR2 using MEK1 as substrate incubated for 40 mins by gamma33P-ATP based scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50626658(CHEMBL5409736)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human PDGFRbeta using MEK1 as substrate incubated for 40 mins by gamma33P-ATP based scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50626657(CHEMBL5405436)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human FGFR1 using MEK1 as substrate incubated for 40 mins by gamma33P-ATP based scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50626658(CHEMBL5409736)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human c-Kit using MEK1 as substrate incubated for 40 mins by gamma33P-ATP based scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50626657(CHEMBL5405436)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human EGFR using MEK1 as substrate incubated for 40 mins by gamma33P-ATP based scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50626658(CHEMBL5409736)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human VEGFR2 using MEK1 as substrate incubated for 40 mins by gamma33P-ATP based scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50626658(CHEMBL5409736)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human FGFR1 using MEK1 as substrate incubated for 40 mins by gamma33P-ATP based scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50626658(CHEMBL5409736)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human FLT3 using MEK1 as substrate incubated for 40 mins by gamma33P-ATP based scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50626658(CHEMBL5409736)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of human CSF1R using MEK1 as substrate incubated for 40 mins by gamma33P-ATP based scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Yeungnam University

Curated by ChEMBL
LigandPNGBDBM50626658(CHEMBL5409736)
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibition of human EGFR using MEK1 as substrate incubated for 40 mins by gamma33P-ATP based scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed