Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50019250
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Innovation Center of Roche

Curated by ChEMBL
LigandPNGBDBM50617145(CHEMBL5394132)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of hERG stably expressed in CHO cells by whole-cell voltage-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Innovation Center of Roche

Curated by ChEMBL
LigandPNGBDBM50617142(CHEMBL5440696)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of hERG stably expressed in CHO cells by whole-cell voltage-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Innovation Center of Roche

Curated by ChEMBL
LigandPNGBDBM50617149(CHEMBL5416588)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of hERG stably expressed in CHO cells by whole-cell voltage-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Innovation Center of Roche

Curated by ChEMBL
LigandPNGBDBM50617141(CHEMBL5436316)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of hERG stably expressed in CHO cells by whole-cell voltage-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Innovation Center of Roche

Curated by ChEMBL
LigandPNGBDBM50617143(CHEMBL5438938)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of hERG stably expressed in CHO cells by whole-cell voltage-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Innovation Center of Roche

Curated by ChEMBL
LigandPNGBDBM50617144(CHEMBL5403174)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of hERG stably expressed in CHO cells by whole-cell voltage-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Innovation Center of Roche

Curated by ChEMBL
LigandPNGBDBM50617146(CHEMBL5431096)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of hERG stably expressed in CHO cells by whole-cell voltage-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Innovation Center of Roche

Curated by ChEMBL
LigandPNGBDBM50617147(CHEMBL5437421)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of hERG stably expressed in CHO cells by whole-cell voltage-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Innovation Center of Roche

Curated by ChEMBL
LigandPNGBDBM50617148(CHEMBL5408647)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of hERG stably expressed in CHO cells by whole-cell voltage-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
China Innovation Center of Roche

Curated by ChEMBL
LigandPNGBDBM50617150(CHEMBL5419005)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of hERG stably expressed in CHO cells by whole-cell voltage-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
China Innovation Center of Roche

Curated by ChEMBL
LigandPNGBDBM50617140(LINVENCORVIR | Linvencorvir | Ro7049389 | RG-7907 ...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCytochrome P450 2D6(Human)
China Innovation Center of Roche

Curated by ChEMBL
LigandPNGBDBM50617140(LINVENCORVIR | Linvencorvir | Ro7049389 | RG-7907 ...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCytochrome P450 2C9(Human)
China Innovation Center of Roche

Curated by ChEMBL
LigandPNGBDBM50617140(LINVENCORVIR | Linvencorvir | Ro7049389 | RG-7907 ...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCytochrome P450 2C19(Human)
China Innovation Center of Roche

Curated by ChEMBL
LigandPNGBDBM50617140(LINVENCORVIR | Linvencorvir | Ro7049389 | RG-7907 ...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCytochrome P450 1A2(Human)
China Innovation Center of Roche

Curated by ChEMBL
LigandPNGBDBM50617140(LINVENCORVIR | Linvencorvir | Ro7049389 | RG-7907 ...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed