Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50018934
TargetCytochrome P450 2A6(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50613945(CHEMBL5289073)
Affinity DataIC50: 40nMAssay Description:Inhibition of CYP2A6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 2A6(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50613946(CHEMBL450963 | 5-Allyloxycoumarin)
Affinity DataIC50: 50nMAssay Description:Inhibition of CYP2A6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 2A6(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50613944(CHEMBL502746)
Affinity DataIC50: 130nMAssay Description:Inhibition of CYP2A6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 2A6(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50613947(CHEMBL448936)
Affinity DataIC50: 170nMAssay Description:Inhibition of CYP2A6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 2A6(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50613943(CHEMBL496547 | 6-Methoxycoumarin)
Affinity DataIC50: 200nMAssay Description:Inhibition of CYP2A6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 2A6(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50041234(9-methoxy-7H-furo[3,2-g]chromen-7-one | CHEMBL416 ...)
Affinity DataIC50: 460nMAssay Description:Inhibition of CYP2A6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 2A6(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50613941(CHEMBL451623)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of CYP2A6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 2A6(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50613942(CHEMBL503184 | 8-Methoxycoumarin)
Affinity DataIC50: 7.47E+3nMAssay Description:Inhibition of CYP2A6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50613941(CHEMBL451623)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50613943(CHEMBL496547 | 6-Methoxycoumarin)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50613942(CHEMBL503184 | 8-Methoxycoumarin)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 2A6(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50613945(CHEMBL5289073)
Affinity DataKi:  10nMAssay Description:Competitive inhibition of CYP2A6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 2A6(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50613946(CHEMBL450963 | 5-Allyloxycoumarin)
Affinity DataKi:  30nMAssay Description:Competitive inhibition of CYP2A6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 2A6(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50613944(CHEMBL502746)
Affinity DataKi:  50nMAssay Description:Mixed type inhibition of CYP2A6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 2A6(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50613947(CHEMBL448936)
Affinity DataKi:  80nMAssay Description:Competitive inhibition of CYP2A6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 2A6(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50041234(9-methoxy-7H-furo[3,2-g]chromen-7-one | CHEMBL416 ...)
Affinity DataKi:  90nMAssay Description:Mixed type inhibition of CYP2A6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 2A6(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50613943(CHEMBL496547 | 6-Methoxycoumarin)
Affinity DataKi:  250nMAssay Description:Competitive inhibition of CYP2A6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 2A6(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50041234(9-methoxy-7H-furo[3,2-g]chromen-7-one | CHEMBL416 ...)
Affinity DataKi:  260nMAssay Description:Non competitive inhibition of CYP2A6 in human liver microsome using coumarin as substrate preincubated with NADPH for 5 mins and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 2A6(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50613941(CHEMBL451623)
Affinity DataKi:  540nMAssay Description:Competitive inhibition of CYP2A6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50041234(9-methoxy-7H-furo[3,2-g]chromen-7-one | CHEMBL416 ...)
Affinity DataKi:  2.20E+3nMAssay Description:Competitive inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 2A6(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50613942(CHEMBL503184 | 8-Methoxycoumarin)
Affinity DataKi:  4.00E+3nMAssay Description:Competitive inhibition of CYP2A6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50041234(9-methoxy-7H-furo[3,2-g]chromen-7-one | CHEMBL416 ...)
Affinity DataKi:  2.50E+4nMAssay Description:Non competitive inhibition of CYP3A4 in human liver microsome using coumarin as substrate preincubated with NADPH for 5 mins and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50613946(CHEMBL450963 | 5-Allyloxycoumarin)
Affinity DataKi:  2.81E+4nMAssay Description:Mixed type inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM12341(US8609708, 31 | CHEMBL359657 | US8609708, 1 | CHEM...)
Affinity DataKi:  2.94E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50613945(CHEMBL5289073)
Affinity DataKi:  4.66E+4nMAssay Description:Mixed type inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50613947(CHEMBL448936)
Affinity DataKi:  4.24E+5nMAssay Description:Non competitive inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Health Sciences University of Hokkaido

Curated by ChEMBL
LigandPNGBDBM50613944(CHEMBL502746)
Affinity DataKi:  4.48E+5nMAssay Description:Non competitive inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed