Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50020771
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Northeast Agricultural University

Curated by ChEMBL
LigandPNGBDBM16111(2-{[2-fluoro-4-(3-methoxyphenyl)phenyl]carbamoyl}c...)
Affinity DataKd:  3.40nMAssay Description:Binding affinity to Escherichia coli NDM-1 assessed as equilibrium dissociation constant measured for 60 sec by bio-layer interferometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Northeast Agricultural University

Curated by ChEMBL
LigandPNGBDBM50633492(CHEMBL4059535)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of Metallo-beta-lactamase NDM-1 (unknown origin) using nitrocefin as substrate incubated for 5 to 10 mins by spectramax reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Northeast Agricultural University

Curated by ChEMBL
LigandPNGBDBM16111(2-{[2-fluoro-4-(3-methoxyphenyl)phenyl]carbamoyl}c...)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of Escherichia coli NDM-1 expressed in Escherichia coli BL21 (DE3) using nitrocefin as substrate by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed