Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50019581
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50540079(CHEMBL4632717)
Affinity DataIC50: 22nMAssay Description:Inhibition of CDK13/Cyclin K (unknown origin) preincubated for 10 mins followed by substrate and ATP addition measured after 200 mins by ADP-Glo lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50528815(CHEMBL4468670)
Affinity DataIC50: 29nMAssay Description:Inhibition of CDK13/Cyclin K (unknown origin) preincubated for 10 mins followed by substrate and ATP addition measured after 200 mins by ADP-Glo lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50528813(CHEMBL4163879 | US20250101023, Example THZ531)
Affinity DataIC50: 40nMAssay Description:Inhibition of CDK13/Cyclin K (unknown origin) preincubated for 10 mins followed by substrate and ATP addition measured after 200 mins by ADP-Glo lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50540079(CHEMBL4632717)
Affinity DataIC50: 53nMAssay Description:Inhibition of CDK12/Cyclin K (unknown origin) preincubated for 10 mins followed by substrate and ATP addition measured after 200 mins by ADP-Glo lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50528815(CHEMBL4468670)
Affinity DataIC50: 74nMAssay Description:Inhibition of CDK12/Cyclin K (unknown origin) preincubated for 10 mins followed by substrate and ATP addition measured after 200 mins by ADP-Glo lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM3175(Bisindolylmaleimide 11b | Ro 31-8220 | CHEMBL6291 ...)
Affinity DataIC50: 143nMAssay Description:Inhibition of CDK12/Cyclin K (unknown origin) preincubated for 10 mins followed by substrate and ATP addition measured after 200 mins by ADP-Glo lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50528813(CHEMBL4163879 | US20250101023, Example THZ531)
Affinity DataIC50: 152nMAssay Description:Inhibition of CDK12/Cyclin K (unknown origin) preincubated for 10 mins followed by substrate and ATP addition measured after 200 mins by ADP-Glo lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50620680(CHEMBL5420867)
Affinity DataIC50: 155nMAssay Description:Inhibition of CDK13/Cyclin K (unknown origin) preincubated for 10 mins followed by substrate and ATP addition measured after 200 mins by ADP-Glo lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50270304(CHEMBL4077071)
Affinity DataIC50: 184nMAssay Description:Inhibition of CDK12/Cyclin K (unknown origin) preincubated for 10 mins followed by substrate and ATP addition measured after 200 mins by ADP-Glo lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50270304(CHEMBL4077071)
Affinity DataIC50: 187nMAssay Description:Inhibition of CDK13/Cyclin K (unknown origin) preincubated for 10 mins followed by substrate and ATP addition measured after 200 mins by ADP-Glo lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM3175(Bisindolylmaleimide 11b | Ro 31-8220 | CHEMBL6291 ...)
Affinity DataIC50: 206nMAssay Description:Inhibition of CDK13/Cyclin K (unknown origin) preincubated for 10 mins followed by substrate and ATP addition measured after 200 mins by ADP-Glo lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50620680(CHEMBL5420867)
Affinity DataIC50: 260nMAssay Description:Inhibition of CDK12/Cyclin K (unknown origin) preincubated for 10 mins followed by substrate and ATP addition measured after 200 mins by ADP-Glo lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50556034(CHEMBL4762845)
Affinity DataIC50: 425nMAssay Description:Inhibition of CDK12/Cyclin K (unknown origin) preincubated for 10 mins followed by substrate and ATP addition measured after 200 mins by ADP-Glo lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50293150(N-(4-(4-methylpiperazin-1-yl)-3-(trifluoromethyl)p...)
Affinity DataIC50: 435nMAssay Description:Inhibition of CDK12/Cyclin K (unknown origin) preincubated for 10 mins followed by substrate and ATP addition measured after 200 mins by ADP-Glo lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM149124(US8962648, 1169 | US8962648, 1168)
Affinity DataIC50: 727nMAssay Description:Inhibition of CDK12/Cyclin K (unknown origin) preincubated for 10 mins followed by substrate and ATP addition measured after 200 mins by ADP-Glo lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50620681(CHEMBL5420897)
Affinity DataIC50: 749nMAssay Description:Inhibition of CDK12/Cyclin K (unknown origin) preincubated for 10 mins followed by substrate and ATP addition measured after 200 mins by ADP-Glo lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed