Compile Data Set for Download or QSAR
Report error Found 54 Enz. Inhib. hit(s) with all data for entry = 50019247
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617125(CHEMBL5398852)
Affinity DataKd:  5.00E+3nMAssay Description:Binding affinity to wild type partial length human PIKFYVE (F1512 to C2098 residues) expressed in mammalian expression system by KdELECT kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617126(CHEMBL5413843)
Affinity DataKd:  270nMAssay Description:Binding affinity to wild type partial length human PIKFYVE (F1512 to C2098 residues) expressed in mammalian expression system by KdELECT kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM86636(JNK-IN-11)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of His-tagged human recombinant JNK2 expressed in baculovirus expression system incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617118(CHEMBL5415466)
Affinity DataIC50: 1nMAssay Description:Inhibition of His-tagged human recombinant JNK2 expressed in baculovirus expression system incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM86636(JNK-IN-11)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of His-tagged human recombinant JNK1 expressed in insect cells incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617112(CHEMBL5432340)
Affinity DataIC50: 2nMAssay Description:Inhibition of His-tagged human recombinant JNK2 expressed in baculovirus expression system incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50590927(Apilimod | Sta-5326 | STA 5326 | STA-5326 | APILIM...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Nano-Luc fused PIKFYVE (unknown origin) expressed in HEK293T cells pretreated for 3 hrs followed by K8-tarcer addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617120(CHEMBL5436350)
Affinity DataIC50: 4nMAssay Description:Inhibition of His-tagged human recombinant JNK2 expressed in baculovirus expression system incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617119(CHEMBL5396061)
Affinity DataIC50: 4nMAssay Description:Inhibition of His-tagged human recombinant JNK2 expressed in baculovirus expression system incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM86633(JNK-IN-8)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of His-tagged human recombinant JNK1 expressed in insect cells incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617126(CHEMBL5413843)
Affinity DataIC50: 5nMAssay Description:Inhibition of His-tagged human recombinant JNK2 expressed in baculovirus expression system incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617124(CHEMBL5410683)
Affinity DataIC50: 5nMAssay Description:Inhibition of His-tagged human recombinant JNK2 expressed in baculovirus expression system incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617110(CHEMBL5397194)
Affinity DataIC50: 5nMAssay Description:Inhibition of His-tagged human recombinant JNK2 expressed in baculovirus expression system incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617121(CHEMBL5436341)
Affinity DataIC50: 7nMAssay Description:Inhibition of His-tagged human recombinant JNK2 expressed in baculovirus expression system incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617109(CHEMBL5410247)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of His-tagged human recombinant JNK2 expressed in baculovirus expression system incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617112(CHEMBL5432340)
Affinity DataIC50: 10nMAssay Description:Inhibition of His-tagged human recombinant JNK1 expressed in insect cells incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617125(CHEMBL5398852)
Affinity DataIC50: 15nMAssay Description:Inhibition of GST-tagged human recombinant p38alpha expressed in Escherichia coli by Lanthascreen Binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617122(CHEMBL5398275)
Affinity DataIC50: 15nMAssay Description:Inhibition of His-tagged human recombinant JNK2 expressed in baculovirus expression system incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617128(CHEMBL5436581)
Affinity DataIC50: 15nMAssay Description:Inhibition of GST-tagged human recombinant p38alpha expressed in Escherichia coli by Lanthascreen Binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617113(CHEMBL5408895)
Affinity DataIC50: 17nMAssay Description:Inhibition of His-tagged human recombinant JNK2 expressed in baculovirus expression system incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617111(CHEMBL5406036)
Affinity DataIC50: 17nMAssay Description:Inhibition of His-tagged human recombinant JNK2 expressed in baculovirus expression system incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617118(CHEMBL5415466)
Affinity DataIC50: 18nMAssay Description:Inhibition of His-tagged human recombinant JNK1 expressed in insect cells incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM86633(JNK-IN-8)
Affinity DataIC50: 19nMAssay Description:Inhibition of His-tagged human recombinant JNK2 expressed in baculovirus expression system incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM86633(JNK-IN-8)
Affinity DataIC50: 26nMAssay Description:Inhibition of Nano-Luc fused JNK1 (unknown origin) expressed in HEK293T cells pretreated for 3 hrs followed by K5-tarcer addition and measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617123(CHEMBL5395598)
Affinity DataIC50: 27nMAssay Description:Inhibition of His-tagged human recombinant JNK2 expressed in baculovirus expression system incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617114(CHEMBL5433713)
Affinity DataIC50: 28nMAssay Description:Inhibition of His-tagged human recombinant JNK2 expressed in baculovirus expression system incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617115(CHEMBL5437715)
Affinity DataIC50: 44nMAssay Description:Inhibition of His-tagged human recombinant JNK2 expressed in baculovirus expression system incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM86633(JNK-IN-8)
Affinity DataIC50: 46nMAssay Description:Inhibition of Nano-Luc fused JNK2 (unknown origin) expressed in HEK293T cells pretreated for 3 hrs followed by K5-tarcer addition and measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617110(CHEMBL5397194)
Affinity DataIC50: 53nMAssay Description:Inhibition of His-tagged human recombinant JNK1 expressed in insect cells incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617121(CHEMBL5436341)
Affinity DataIC50: 62nMAssay Description:Inhibition of His-tagged human recombinant JNK1 expressed in insect cells incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617119(CHEMBL5396061)
Affinity DataIC50: 67nMAssay Description:Inhibition of His-tagged human recombinant JNK1 expressed in insect cells incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617125(CHEMBL5398852)
Affinity DataIC50: 70nMAssay Description:Inhibition of His-tagged human recombinant JNK2 expressed in baculovirus expression system incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617120(CHEMBL5436350)
Affinity DataIC50: 74nMAssay Description:Inhibition of His-tagged human recombinant JNK1 expressed in insect cells incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617125(CHEMBL5398852)
Affinity DataIC50: 84nMAssay Description:Inhibition of GST-tagged human recombinant JNK3 expressed in insect cells incubated for 1 hr in presence of ATP by Z'-lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617124(CHEMBL5410683)
Affinity DataIC50: 89nMAssay Description:Inhibition of His-tagged human recombinant JNK1 expressed in insect cells incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617125(CHEMBL5398852)
Affinity DataIC50: 132nMAssay Description:Inhibition of Nano-Luc fused JNK2 (unknown origin) expressed in HEK293T cells pretreated for 3 hrs followed by K5-tarcer addition and measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617117(CHEMBL5415188)
Affinity DataIC50: 142nMAssay Description:Inhibition of His-tagged human recombinant JNK2 expressed in baculovirus expression system incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617122(CHEMBL5398275)
Affinity DataIC50: 160nMAssay Description:Inhibition of His-tagged human recombinant JNK1 expressed in insect cells incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617126(CHEMBL5413843)
Affinity DataIC50: 166nMAssay Description:Inhibition of His-tagged human recombinant JNK1 expressed in insect cells incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617123(CHEMBL5395598)
Affinity DataIC50: 237nMAssay Description:Inhibition of His-tagged human recombinant JNK1 expressed in insect cells incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617114(CHEMBL5433713)
Affinity DataIC50: 256nMAssay Description:Inhibition of His-tagged human recombinant JNK1 expressed in insect cells incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617126(CHEMBL5413843)
Affinity DataIC50: 292nMAssay Description:Inhibition of Nano-Luc fused PIKFYVE (unknown origin) expressed in HEK293T cells pretreated for 3 hrs followed by K8-tarcer addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617113(CHEMBL5408895)
Affinity DataIC50: 387nMAssay Description:Inhibition of His-tagged human recombinant JNK1 expressed in insect cells incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617111(CHEMBL5406036)
Affinity DataIC50: 470nMAssay Description:Inhibition of His-tagged human recombinant JNK1 expressed in insect cells incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617115(CHEMBL5437715)
Affinity DataIC50: 475nMAssay Description:Inhibition of His-tagged human recombinant JNK1 expressed in insect cells incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617116(CHEMBL5406812)
Affinity DataIC50: 483nMAssay Description:Inhibition of His-tagged human recombinant JNK2 expressed in baculovirus expression system incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617109(CHEMBL5410247)
Affinity DataIC50: 724nMAssay Description:Inhibition of His-tagged human recombinant JNK1 expressed in insect cells incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617117(CHEMBL5415188)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of His-tagged human recombinant JNK1 expressed in insect cells incubated for 1 hr in presence of ATP by Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617125(CHEMBL5398852)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Nano-Luc fused JNK1 (unknown origin) expressed in HEK293T cells pretreated for 3 hrs followed by K5-tarcer addition and measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50617128(CHEMBL5436581)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Nano-Luc fused JNK2 (unknown origin) expressed in HEK293T cells pretreated for 3 hrs followed by K5-tarcer addition and measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
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