Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50019246
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617104(CHEMBL5395724)
Affinity DataIC50: 3.75E+3nMAssay Description:Inhibition of Leishmania donovani Top1 assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by agarose gel electrophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617108(CHEMBL5407977)
Affinity DataIC50: 5.25E+3nMAssay Description:Inhibition of Leishmania donovani Top1 assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by agarose gel electrophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617096(CHEMBL5427724)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of Leishmania donovani Top1 assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by agarose gel electrophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617104(CHEMBL5395724)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of recombinant Top1 in Leishmania donovani Ag83 whole cell extract assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617094(CHEMBL5431960)
Affinity DataIC50: 6.75E+3nMAssay Description:Inhibition of Leishmania donovani Top1 assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by agarose gel electrophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617097(CHEMBL5413499)
Affinity DataIC50: 7.25E+3nMAssay Description:Inhibition of Leishmania donovani Top1 assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by agarose gel electrophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617095(CHEMBL5434027)
Affinity DataIC50: 7.25E+3nMAssay Description:Inhibition of Leishmania donovani Top1 assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by agarose gel electrophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617103(CHEMBL5422628)
Affinity DataIC50: 8.52E+3nMAssay Description:Inhibition of Leishmania donovani Top1 assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by agarose gel electrophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617104(CHEMBL5395724)
Affinity DataIC50: 8.75E+3nMAssay Description:Inhibition of recombinant Top1 in Antimony resistant Leishmania donovani BHU575 whole cell extract assessed as relaxation of supercoiled pBluescript ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50008923(4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaz...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of Leishmania donovani Top1 assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by agarose gel electrophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617107(CHEMBL5397183)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Leishmania donovani Top1 assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by agarose gel electrophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617088(CHEMBL5423477)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Leishmania donovani Top1 assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by agarose gel electrophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617089(CHEMBL5434098)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Leishmania donovani Top1 assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by agarose gel electrophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617090(CHEMBL5396760)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Leishmania donovani Top1 assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by agarose gel electrophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617093(CHEMBL5394451)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Leishmania donovani Top1 assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by agarose gel electrophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617106(CHEMBL5393978)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Leishmania donovani Top1 assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by agarose gel electrophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617105(CHEMBL5405905)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Leishmania donovani Top1 assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by agarose gel electrophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617091(CHEMBL5431403)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Leishmania donovani Top1 assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by agarose gel electrophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617092(CHEMBL5403760)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Leishmania donovani Top1 assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by agarose gel electrophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617102(CHEMBL5428175)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Leishmania donovani Top1 assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by agarose gel electrophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617101(CHEMBL5394200)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Leishmania donovani Top1 assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by agarose gel electrophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617100(CHEMBL5405408)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Leishmania donovani Top1 assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by agarose gel electrophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617099(CHEMBL5430320)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Leishmania donovani Top1 assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by agarose gel electrophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617098(CHEMBL5427528)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Leishmania donovani Top1 assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by agarose gel electrophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617108(CHEMBL5407977)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant Top1 in Leishmania donovani Ag83 whole cell extract assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617096(CHEMBL5427724)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of recombinant Top1 in Leishmania donovani Ag83 whole cell extract assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617094(CHEMBL5431960)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of recombinant Top1 in Leishmania donovani Ag83 whole cell extract assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617097(CHEMBL5413499)
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of recombinant Top1 in Leishmania donovani Ag83 whole cell extract assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50617095(CHEMBL5434027)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of recombinant Top1 in Leishmania donovani Ag83 whole cell extract assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetDNA topoisomerase I(Leishmania donovani)
Indian Association for the Cultivation of Science

Curated by ChEMBL
LigandPNGBDBM50008923(4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaz...)
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of recombinant Top1 in Leishmania donovani Ag83 whole cell extract assessed as relaxation of supercoiled pBluescript SK(+) DNA measured by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed