Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50019244
TargetEpidermal growth factor receptor(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50617086(CHEMBL5398727)
Affinity DataIC50: 100nMAssay Description:Inhibition of wild type EGFR (unknown origin) preincubated for 5 mins followed by substrate and ATP addition and further incubated for 30 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 320nMAssay Description:Inhibition of wild type EGFR (unknown origin) preincubated for 5 mins followed by substrate and ATP addition and further incubated for 30 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50617086(CHEMBL5398727)
Affinity DataIC50: 4.02E+3nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by substrate and ATP addition and further incubated for 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 2.14E+4nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by substrate and ATP addition and further incubated for 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMedPDB3D3D Structure (crystal)