Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50020618
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50631999(CHEMBL5396216)
Affinity DataIC50: 16nMAssay Description:Binding affinity to wild type FLAG-tagged PKM2 in human PA-1 cells measured for 72 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50631999(CHEMBL5396216)
Affinity DataIC50: 93nMAssay Description:Binding affinity to PKM2 C474S mutant in human PA-1 cells measured for 72 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50631998(CHEMBL5399474)
Affinity DataIC50: 122nMAssay Description:Inhibition of human PKM2 assessed as ATP production incubated for 10 mins by Celltiter-glo luminescent analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50631999(CHEMBL5396216)
Affinity DataIC50: 129nMAssay Description:Binding affinity to PKM2 C474A mutant in human PA-1 cells measured for 72 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50631995(CHEMBL5404355)
Affinity DataIC50: 139nMAssay Description:Inhibition of human PKM2 assessed as ATP production incubated for 10 mins by Celltiter-glo luminescent analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50631992(CHEMBL5413275)
Affinity DataIC50: 230nMAssay Description:Inhibition of human PKM2 assessed as ATP production incubated for 10 mins by Celltiter-glo luminescent analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50631998(CHEMBL5399474)
Affinity DataIC50: 250nMAssay Description:Inhibition of human PKM2 assessed as ATP production incubated for 10 mins in presence of beta-mercaptoethanol by Celltiter-glo luminescent analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50631996(CHEMBL5440683)
Affinity DataIC50: 285nMAssay Description:Inhibition of human PKM2 assessed as ATP production incubated for 10 mins by Celltiter-glo luminescent analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50033731(5,8-Dihydroxy-2-(1-hydroxy-4-methyl-pent-3-enyl)-[...)
Affinity DataIC50: 301nMAssay Description:Binding affinity to wild type FLAG-tagged PKM2 in human PA-1 cells measured for 72 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50631997(CHEMBL5400237)
Affinity DataIC50: 326nMAssay Description:Inhibition of human PKM2 assessed as ATP production incubated for 10 mins by Celltiter-glo luminescent analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50033731(5,8-Dihydroxy-2-(1-hydroxy-4-methyl-pent-3-enyl)-[...)
Affinity DataIC50: 326nMAssay Description:Binding affinity to PKM2 C474S mutant in human PA-1 cells measured for 72 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50033731(5,8-Dihydroxy-2-(1-hydroxy-4-methyl-pent-3-enyl)-[...)
Affinity DataIC50: 381nMAssay Description:Binding affinity to PKM2 C474A mutant in human PA-1 cells measured for 72 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50631995(CHEMBL5404355)
Affinity DataIC50: 586nMAssay Description:Inhibition of human PKM2 assessed as ATP production incubated for 10 mins in presence of beta-mercaptoethanol by Celltiter-glo luminescent analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50632001(CHEMBL5412106)
Affinity DataIC50: 671nMAssay Description:Inhibition of human PKM2 assessed as ATP production incubated for 10 mins by Celltiter-glo luminescent analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50631994(CHEMBL5410552)
Affinity DataIC50: 999nMAssay Description:Inhibition of human PKM2 assessed as ATP production incubated for 10 mins by Celltiter-glo luminescent analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50631992(CHEMBL5413275)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of human PKM2 assessed as ATP production incubated for 10 mins in presence of beta-mercaptoethanol by Celltiter-glo luminescent analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50631994(CHEMBL5410552)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of human PKM2 assessed as ATP production incubated for 10 mins in presence of beta-mercaptoethanol by Celltiter-glo luminescent analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50631997(CHEMBL5400237)
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of human PKM2 assessed as ATP production incubated for 10 mins in presence of beta-mercaptoethanol by Celltiter-glo luminescent analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50033731(5,8-Dihydroxy-2-(1-hydroxy-4-methyl-pent-3-enyl)-[...)
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of human PKM1 assessed as ATP production incubated for 10 mins by Celltiter-glo luminescent analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50631996(CHEMBL5440683)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of human PKM2 assessed as ATP production incubated for 10 mins in presence of beta-mercaptoethanol by Celltiter-glo luminescent analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50632001(CHEMBL5412106)
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of human PKM2 assessed as ATP production incubated for 10 mins in presence of beta-mercaptoethanol by Celltiter-glo luminescent analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50033731(5,8-Dihydroxy-2-(1-hydroxy-4-methyl-pent-3-enyl)-[...)
Affinity DataIC50: 2.58E+3nMAssay Description:Inhibition of human PKM2 assessed as ATP production incubated for 10 mins by Celltiter-glo luminescent analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50033731(5,8-Dihydroxy-2-(1-hydroxy-4-methyl-pent-3-enyl)-[...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PKM2 assessed as ATP production incubated for 10 mins in presence of beta-mercaptoethanol by Celltiter-glo luminescent analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50631999(CHEMBL5396216)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PKM2 assessed as ATP production incubated for 10 mins in presence of beta-mercaptoethanol by Celltiter-glo luminescent analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50632000(CHEMBL5404224)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PKM2 assessed as ATP production incubated for 10 mins in presence of beta-mercaptoethanol by Celltiter-glo luminescent analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50632000(CHEMBL5404224)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PKM2 assessed as ATP production incubated for 10 mins by Celltiter-glo luminescent analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50631999(CHEMBL5396216)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PKM2 assessed as ATP production incubated for 10 mins by Celltiter-glo luminescent analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50631993(CHEMBL5417154)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PKM2 assessed as ATP production incubated for 10 mins in presence of beta-mercaptoethanol by Celltiter-glo luminescent analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50631993(CHEMBL5417154)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PKM2 assessed as ATP production incubated for 10 mins by Celltiter-glo luminescent analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed