Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50018176
TargetProstaglandin E synthase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50405790(CHEMBL5284121)
Affinity DataIC50: 150nMAssay Description:Inhibition of mPGES-1 activity in IL-1beta stimulated human A549 microsomal preparation using PGH2 as substrate assessed as inhibition of PGE2 synthe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProstaglandin E synthase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50405760(CHEMBL5284133)
Affinity DataIC50: 200nMAssay Description:Inhibition of mPGES-1 activity in IL-1beta stimulated human A549 microsomal preparation using PGH2 as substrate assessed as inhibition of PGE2 synthe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProstaglandin E synthase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50405791(CHEMBL5285589)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of mPGES-1 activity in IL-1beta stimulated human A549 microsomal preparation using PGH2 as substrate assessed as inhibition of PGE2 synthe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProstaglandin E synthase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50405761(CHEMBL5274544)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of mPGES-1 activity in IL-1beta stimulated human A549 microsomal preparation using PGH2 as substrate assessed as inhibition of PGE2 synthe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50405790(CHEMBL5284121)
Affinity DataIC50: 2.43E+4nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50405761(CHEMBL5274544)
Affinity DataIC50: 4.28E+4nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed