Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50019279
TargetNitric oxide synthase, inducible(Human)
University of Granada

Curated by ChEMBL
LigandPNGBDBM50617539(CHEMBL5396622)
Affinity DataIC50: 65nMAssay Description:Inhibition of N-terminal his6-tagged recombinant human iNOS expressed in Escherichia coli preincubated for 15 mins followed by NADPH addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNitric oxide synthase, inducible(Human)
University of Granada

Curated by ChEMBL
LigandPNGBDBM50226527(N-[3-(aminomethyl)benzyl]ethanimidamide | N-(3-Ami...)
Affinity DataIC50: 81nMAssay Description:Inhibition of N-terminal his6-tagged recombinant human iNOS expressed in Escherichia coli preincubated for 15 mins followed by NADPH addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNitric oxide synthase, inducible(Human)
University of Granada

Curated by ChEMBL
LigandPNGBDBM50226527(N-[3-(aminomethyl)benzyl]ethanimidamide | N-(3-Ami...)
Affinity DataIC50: 200nMAssay Description:Inhibition of iNOS (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNitric oxide synthase, inducible(Human)
University of Granada

Curated by ChEMBL
LigandPNGBDBM50617540(CHEMBL5403837)
Affinity DataIC50: 832nMAssay Description:Inhibition of N-terminal his6-tagged recombinant human iNOS expressed in Escherichia coli preincubated for 15 mins followed by NADPH addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNitric oxide synthase, inducible(Human)
University of Granada

Curated by ChEMBL
LigandPNGBDBM50230993(CHEMBL256147 | 2-Amino-5-(N'-methyl-guanidino)-pen...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of iNOS (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNitric oxide synthase, inducible(Human)
University of Granada

Curated by ChEMBL
LigandPNGBDBM50098937(CHEMBL7890 | CHEMBL1256014 | methyl (2S)-2-amino-5...)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of iNOS (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of Granada

Curated by ChEMBL
LigandPNGBDBM50617539(CHEMBL5396622)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full length N-terminal his-tagged bovine eNOS (2 to 1205 residues) expressed in Escherichia coli preincubated for 15 mins followed by N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of Granada

Curated by ChEMBL
LigandPNGBDBM50617540(CHEMBL5403837)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full length N-terminal his-tagged bovine eNOS (2 to 1205 residues) expressed in Escherichia coli preincubated for 15 mins followed by N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
University of Granada

Curated by ChEMBL
LigandPNGBDBM50226527(N-[3-(aminomethyl)benzyl]ethanimidamide | N-(3-Ami...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of full length N-terminal his-tagged bovine eNOS (2 to 1205 residues) expressed in Escherichia coli preincubated for 15 mins followed by N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed