Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50015864
Target14 kDa phosphohistidine phosphatase(Human)
Ulsan National Institute of Science and Technology (UNIST)

Curated by ChEMBL
LigandPNGBDBM50186231([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of human PHPT1 expressed in Escherichia coli BL21 (DE3) using pNPP as substrate incubated for 1 hr by multimode microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target14 kDa phosphohistidine phosphatase(Human)
Ulsan National Institute of Science and Technology (UNIST)

Curated by ChEMBL
LigandPNGBDBM50186231([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...)
Affinity DataKi:  1.83E+5nMAssay Description:Inhibition of human PHPT1 expressed in Escherichia coli BL21 (DE3) using pNPP as substrate assessed as inhibition constant by reciprocal analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target14 kDa phosphohistidine phosphatase(Human)
Ulsan National Institute of Science and Technology (UNIST)

Curated by ChEMBL
LigandPNGBDBM50220832(CHEMBL8211 | N-ethylmaleimide)
Affinity DataKi:  2.09E+5nMAssay Description:Inhibition of human PHPT1 expressed in Escherichia coli BL21 (DE3) using pNPP as substrate assessed as inhibition constant by reciprocal analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed