Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50016228
TargetEpidermal growth factor receptor(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50555575(Lazertinib | Yh25448 | C-18112003-G | GNS-1480 | G...)
Affinity DataKi:  34nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (669 to 1210 residues) (unknown origin) L858R/T790M mutant expressed in baculovirus infect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50238177(CHEMBL4098072)
Affinity DataKi:  99nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR wild type (669 to 1210 residues) expressed in baculovirus infected Sf21 insect cells insec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50238177(CHEMBL4098072)
Affinity DataKi:  142nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HER2 wild type (679 to 1255 residues) expressed in baculovirus infected Sf9 insect cells using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50238177(CHEMBL4098072)
Affinity DataKi:  224nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (669 to 1210 residues) (unknown origin) L858R/T790M mutant expressed in baculovirus infect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataKi:  256nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (669 to 1210 residues) (unknown origin) L858R/T790M mutant expressed in baculovirus infect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50555575(Lazertinib | Yh25448 | C-18112003-G | GNS-1480 | G...)
Affinity DataKi:  271nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR wild type (669 to 1210 residues) expressed in baculovirus infected Sf21 insect cells insec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataKi:  434nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR wild type (669 to 1210 residues) expressed in baculovirus infected Sf21 insect cells insec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50555575(Lazertinib | Yh25448 | C-18112003-G | GNS-1480 | G...)
Affinity DataKi:  437nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HER2 wild type (679 to 1255 residues) expressed in baculovirus infected Sf9 insect cells using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed