Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50018686
TargetCyclin-dependent kinase 4(Human)
University of Kwazulu-Natal (Westville)

Curated by ChEMBL
LigandPNGBDBM50611418(CHEMBL5271655)
Affinity DataIC50: 20nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Kwazulu-Natal (Westville)

Curated by ChEMBL
LigandPNGBDBM50611421(CHEMBL5276637)
Affinity DataIC50: 70nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Kwazulu-Natal (Westville)

Curated by ChEMBL
LigandPNGBDBM50611421(CHEMBL5276637)
Affinity DataIC50: 160nMAssay Description:Inhibition of CDK5/p25 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Kwazulu-Natal (Westville)

Curated by ChEMBL
LigandPNGBDBM153386(2-(4,5-Dibromo-1H-pyrrole-2-carbonyl)-N-(4-chlorop...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of MMP-2 (unknown origin) using succinylated gelatin as substrate incubated for 80 mins by microplate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
University of Kwazulu-Natal (Westville)

Curated by ChEMBL
LigandPNGBDBM50611428(CHEMBL5287845)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent ubiquitination in presence of ATP measured after 13 hrs by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
University of Kwazulu-Natal (Westville)

Curated by ChEMBL
LigandPNGBDBM50611427(CHEMBL5279459)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent ubiquitination in presence of ATP measured after 13 hrs by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
University of Kwazulu-Natal (Westville)

Curated by ChEMBL
LigandPNGBDBM50611426(CHEMBL5267416)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent ubiquitination in presence of ATP measured after 13 hrs by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
University of Kwazulu-Natal (Westville)

Curated by ChEMBL
LigandPNGBDBM50611425(CHEMBL5280295)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent ubiquitination in presence of ATP measured after 13 hrs by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
University of Kwazulu-Natal (Westville)

Curated by ChEMBL
LigandPNGBDBM50611424(CHEMBL5274960)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent ubiquitination in presence of ATP measured after 13 hrs by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
University of Kwazulu-Natal (Westville)

Curated by ChEMBL
LigandPNGBDBM50611423(CHEMBL5269966)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent ubiquitination in presence of ATP measured after 13 hrs by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
University of Kwazulu-Natal (Westville)

Curated by ChEMBL
LigandPNGBDBM50611422(CHEMBL5289025)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of Cbl-b (unknown origin) assessed as inhibition of Cbl-b dependent ubiquitination in presence of ATP measured after 13 hrs by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
University of Kwazulu-Natal (Westville)

Curated by ChEMBL
LigandPNGBDBM50509086(CHEMBL4539558)
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of c-ErbB-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetVIP peptides(Human)
University of Kwazulu-Natal (Westville)

Curated by ChEMBL
LigandPNGBDBM50611420(CHEMBL5285378)
Affinity DataIC50: 1.92E+4nMAssay Description:Displacement of [125I]-VIP from Vasoactive intestinal peptide (unknown origin) incubated for 120 mins by gamma scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetVIP peptides(Human)
University of Kwazulu-Natal (Westville)

Curated by ChEMBL
LigandPNGBDBM50611419(SCEPTRIN | CHEBI:80954 | Sceptrin)
Affinity DataIC50: 1.98E+4nMAssay Description:Displacement of [125I]-VIP from Vasoactive intestinal peptide (unknown origin) incubated for 120 mins by gamma scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
University of Kwazulu-Natal (Westville)

Curated by ChEMBL
LigandPNGBDBM50509084(CHEMBL4531006)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of c-ErbB-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 4(Human)
University of Kwazulu-Natal (Westville)

Curated by ChEMBL
LigandPNGBDBM50509086(CHEMBL4539558)
Affinity DataIC50: 2.96E+4nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
University of Kwazulu-Natal (Westville)

Curated by ChEMBL
LigandPNGBDBM50509088(CHEMBL4575427)
Affinity DataIC50: 3.79E+4nMAssay Description:Inhibition of c-ErbB-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
University of Kwazulu-Natal (Westville)

Curated by ChEMBL
LigandPNGBDBM50509085(TAUROACIDIN A)
Affinity DataIC50: 3.79E+4nMAssay Description:Inhibition of c-ErbB-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
University of Kwazulu-Natal (Westville)

Curated by ChEMBL
LigandPNGBDBM50509085(TAUROACIDIN A)
Affinity DataIC50: 4.46E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
University of Kwazulu-Natal (Westville)

Curated by ChEMBL
LigandPNGBDBM50509088(CHEMBL4575427)
Affinity DataIC50: 4.46E+4nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 4(Human)
University of Kwazulu-Natal (Westville)

Curated by ChEMBL
LigandPNGBDBM50509084(CHEMBL4531006)
Affinity DataIC50: 9.85E+4nMAssay Description:Inhibition of CDK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed