Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50017502
TargetC-C chemokine receptor type 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602353(CHEMBL5171331)
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602350(CHEMBL5180628)
Affinity DataIC50: 4.40nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602351(CHEMBL5177519)
Affinity DataIC50: 5.30nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50334986(4,4-Difluoro-cyclohexanecarboxylic acid {(S)-3-[(1...)
Affinity DataIC50: 8nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602343(CHEMBL5205216)
Affinity DataIC50: 8nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602354(CHEMBL5209067)
Affinity DataIC50: 8.30nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602349(CHEMBL5200961)
Affinity DataIC50: 9.30nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602340(CHEMBL5185201)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602336(CHEMBL5176665)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602355(CHEMBL5175220)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM314060(US10167299, PF-232798The)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602345(CHEMBL5178121)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602344(CHEMBL5204027)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602339(CHEMBL5197247)
Affinity DataIC50: 32nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602337(CHEMBL5178495)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602342(CHEMBL5208613)
Affinity DataIC50: 45nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50464151(CHEMBL4240742)
Affinity DataIC50: 67nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602341(CHEMBL5205626)
Affinity DataIC50: 73nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602352(CHEMBL5184527)
Affinity DataIC50: 680nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602338(CHEMBL5184978)
Affinity DataIC50: 1.38E+3nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50334986(4,4-Difluoro-cyclohexanecarboxylic acid {(S)-3-[(1...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602348(CHEMBL5171807)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602346(CHEMBL5169473)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602347(CHEMBL5194455)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293 cells co-expressing Galpha16 assessed as intracellular calcium change incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCytochrome P450 2C9(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50334986(4,4-Difluoro-cyclohexanecarboxylic acid {(S)-3-[(1...)
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50334986(4,4-Difluoro-cyclohexanecarboxylic acid {(S)-3-[(1...)
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using testosterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602355(CHEMBL5175220)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using testosterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602354(CHEMBL5209067)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using testosterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602355(CHEMBL5175220)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602354(CHEMBL5209067)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using midazolam as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCytochrome P450 2D6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602355(CHEMBL5175220)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCytochrome P450 2D6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602354(CHEMBL5209067)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCytochrome P450 2D6(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50334986(4,4-Difluoro-cyclohexanecarboxylic acid {(S)-3-[(1...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCytochrome P450 2C19(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602355(CHEMBL5175220)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCytochrome P450 2C19(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602354(CHEMBL5209067)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCytochrome P450 2C19(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50334986(4,4-Difluoro-cyclohexanecarboxylic acid {(S)-3-[(1...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCytochrome P450 2C9(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602355(CHEMBL5175220)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCytochrome P450 2C9(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602354(CHEMBL5209067)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCytochrome P450 1A2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602355(CHEMBL5175220)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCytochrome P450 1A2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50602354(CHEMBL5209067)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCytochrome P450 1A2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50334986(4,4-Difluoro-cyclohexanecarboxylic acid {(S)-3-[(1...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed