Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50015858
TargetLanosterol 14-alpha demethylase(Yeast)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50590139(CHEMBL5196919)
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of candida albicans CYP51 using 7-ethoxyresorufin as fluorescent substrate incubated for 10 mins in the presence of NADPH by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetLanosterol 14-alpha demethylase(Yeast)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM25817(Fungata | Diflucan | Fluconazole (f) | cid_3365 | ...)
Affinity DataIC50: 2.89E+4nMAssay Description:Inhibition of candida albicans CYP51 using 7-ethoxyresorufin as fluorescent substrate incubated for 10 mins in the presence of NADPH by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50590139(CHEMBL5196919)
Affinity DataIC50: 3.05E+7nMAssay Description:Inhibition of human CYP3A4 using luciferin-IPA as substrate preincubated for 10 mins followed by NADPH addition and measured after 30 mins by lumines...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed