Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50020719
TargetSolute carrier family 22 member 11(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 37953BDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of OAT4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 37953BDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of URAT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 290431BDBM290431(RDEA3170 | US10100016, Verinurad (RDEA3170) | CAS ...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human URT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134635BDBM50134635(CHEMBL3746329 | US9637484, 3)
Affinity DataIC50: 34nMAssay Description:Inhibition of URAT1 (unknown origin) assessed as decrease in uric acid levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50561689BDBM50561689(Dotinurad | Fyu-981)
Affinity DataIC50: 37nMAssay Description:Inhibition of ABCG2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50633039BDBM50633039(CHEMBL5412360)
Affinity DataIC50: 590nMAssay Description:Inhibition of XO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50159609BDBM50159609(2-(4-Fluoro-phenyl)-benzo[h]chromen-4-one | CHEMBL...)
Affinity DataIC50: 620nMAssay Description:Inhibition of XO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338853BDBM50338853(1-(3-(Furan-2-yl)-4,5-dihydro-5-(pyridin-4-yl)pyra...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of XO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50633040BDBM50633040(CHEMBL5434604)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of XO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50346917BDBM50346917(CHEMBL1795523)
Affinity DataIC50: 2.17E+4nMAssay Description:Inhibition of XO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Peking University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50320491BDBM50320491(CHEMBL1164729 | 2-(3-CYANO-4-ISOBUTOXY-PHENYL)-4-M...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of XO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed