Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50018545
TargetHistone-lysine N-methyltransferase EZH2(Human)
Second Military Medical University (Naval Medical University)

Curated by ChEMBL
LigandPNGBDBM50609425(CHEMBL5280243)
Affinity DataEC50:  200nMAssay Description:Induction of degradation of EZH2 in human EOL1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Second Military Medical University (Naval Medical University)

Curated by ChEMBL
LigandPNGBDBM50609425(CHEMBL5280243)
Affinity DataEC50:  1.50E+3nMAssay Description:Induction of degradation of EZH2 in human MV4-11 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Second Military Medical University (Naval Medical University)

Curated by ChEMBL
LigandPNGBDBM50609427(CHEMBL5289464)
Affinity DataEC50:  140nMAssay Description:Induction of degradation of EZH2 degradation in human MDA-MB-453 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Second Military Medical University (Naval Medical University)

Curated by ChEMBL
LigandPNGBDBM50609428(CHEMBL5266272)
Affinity DataEC50:  7.10nMAssay Description:Induction of degradation NAMPT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetAurora kinase A(Human)
Second Military Medical University (Naval Medical University)

Curated by ChEMBL
LigandPNGBDBM50609429(CHEMBL5278315)
Affinity DataEC50:  28nMAssay Description:Induction of degradation of AURORA-A in human MV4-11 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetFocal adhesion kinase 1(Human)
Second Military Medical University (Naval Medical University)

Curated by ChEMBL
LigandPNGBDBM50520571(CHEMBL4447794)
Affinity DataEC50:  3nMAssay Description:Induction of degradation of Fak in human PC-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Human)
Second Military Medical University (Naval Medical University)

Curated by ChEMBL
LigandPNGBDBM50609430(CHEMBL5275279)
Affinity DataEC50:  0.270nMAssay Description:Induction of degradation of FKBP12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Second Military Medical University (Naval Medical University)

Curated by ChEMBL
LigandPNGBDBM50609431(CHEMBL5286211)
Affinity DataEC50:  33nMAssay Description:Induction of degradation of USP7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetFocal adhesion kinase 1(Human)
Second Military Medical University (Naval Medical University)

Curated by ChEMBL
LigandPNGBDBM418817(US10450297, Example 317 | US10450297, Example 318 ...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetFocal adhesion kinase 1(Human)
Second Military Medical University (Naval Medical University)

Curated by ChEMBL
LigandPNGBDBM50520571(CHEMBL4447794)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Second Military Medical University (Naval Medical University)

Curated by ChEMBL
LigandPNGBDBM50609425(CHEMBL5280243)
Affinity DataIC50: 7nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Second Military Medical University (Naval Medical University)

Curated by ChEMBL
LigandPNGBDBM50609428(CHEMBL5266272)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of NAMPT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Second Military Medical University (Naval Medical University)

Curated by ChEMBL
LigandPNGBDBM50609426(CHEMBL5289343)
Affinity DataIC50: 13nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Second Military Medical University (Naval Medical University)

Curated by ChEMBL
LigandPNGBDBM50536555(CHEMBL4532174)
Affinity DataIC50: 44nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed