Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50018779
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612481(CHEMBL5271398)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50546900(CHEMBL4756866)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612476(CHEMBL5277301)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612472(CHEMBL5284974)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612468(CHEMBL5287151)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612477(CHEMBL5289202)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612478(CHEMBL5269373)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612464(CHEMBL5279672)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612475(CHEMBL5278085)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612485(CHEMBL5289441)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612465(CHEMBL5273217)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612469(CHEMBL5277066)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612488(CHEMBL5290258)
Affinity DataIC50: 10nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612490(CHEMBL5268478)
Affinity DataIC50: 10nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612470(CHEMBL5291373)
Affinity DataIC50: 11nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612479(CHEMBL5285786)
Affinity DataIC50: 11nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612463(CHEMBL5267010)
Affinity DataIC50: 11nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612491(CHEMBL5267727)
Affinity DataIC50: 11nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612482(CHEMBL5282615)
Affinity DataIC50: 11nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612487(CHEMBL5290341)
Affinity DataIC50: 12nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612493(CHEMBL5266247)
Affinity DataIC50: 12nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612480(CHEMBL5268476)
Affinity DataIC50: 12nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612471(CHEMBL5282586)
Affinity DataIC50: 12nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612466(CHEMBL5285533)
Affinity DataIC50: 12nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612474(CHEMBL5272958)
Affinity DataIC50: 13nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612486(CHEMBL5278304)
Affinity DataIC50: 14nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612492(CHEMBL5272326)
Affinity DataIC50: 15nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612483(CHEMBL5282047)
Affinity DataIC50: 16nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612467(CHEMBL5269609)
Affinity DataIC50: 16nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612489(CHEMBL5284756)
Affinity DataIC50: 17nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612484(CHEMBL5287955)
Affinity DataIC50: 19nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50612473(CHEMBL5270485)
Affinity DataIC50: 20nMAssay Description:Inhibition of human URAT1 mediated 14C-uric acid uptake expressed in HEK293 cells using 14C-uric acid as substrate incubated for 30 mins by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
LigandPNGBDBM50612472(CHEMBL5284974)
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of GLUT9 (unknown origin) transfected in HEK293 cells assessed as inhibition of uric acid-induced current by whole cell patch clamp analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed