Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50018041
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50239952(CHEMBL4081997)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607155(CHEMBL5220395)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagen alpha-1(II) chain(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50239952(CHEMBL4081997)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of Collagen-II-alpha 1 (unknown origin) incubated for 22 hrs by Coomassie blue staining based SDS-PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607150(CHEMBL5218895)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50239951(CHEMBL4100008)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607152(CHEMBL5218777)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607153(CHEMBL5219237)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607146(CHEMBL5220833)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607154(CHEMBL5219770)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607145(CHEMBL5220816)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607144(CHEMBL5219839)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607151(CHEMBL5219063)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607143(CHEMBL5220533)
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607148(CHEMBL5220881)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607167(CHEMBL5220323)
Affinity DataIC50: 42nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607147(CHEMBL5220661)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607149(CHEMBL5219437)
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607160(CHEMBL5219938)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607161(CHEMBL5218856)
Affinity DataIC50: 235nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607168(CHEMBL5219025)
Affinity DataIC50: 240nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607166(CHEMBL5220923)
Affinity DataIC50: 571nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50239952(CHEMBL4081997)
Affinity DataIC50: 600nMAssay Description:Inhibition of MMP-8 (unknown origin) using fTHP-15(FAM) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607159(CHEMBL5219911)
Affinity DataIC50: 623nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50239952(CHEMBL4081997)
Affinity DataIC50: 730nMAssay Description:Inhibition of MMP-2 (unknown origin) using fTHP-15(FAM) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607163(CHEMBL5219954)
Affinity DataIC50: 813nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607146(CHEMBL5220833)
Affinity DataIC50: 832nMAssay Description:Inhibition of MMP-2 (unknown origin) using fTHP-15(FAM) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607157(CHEMBL5219868)
Affinity DataIC50: 855nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607165(CHEMBL5218956)
Affinity DataIC50: 997nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607158(CHEMBL5219625)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607162(CHEMBL5219537)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607144(CHEMBL5219839)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of MMP-2 (unknown origin) using fTHP-15(FAM) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetInterstitial collagenase(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50239951(CHEMBL4100008)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of MMP-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607146(CHEMBL5220833)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of MMP-8 (unknown origin) using fTHP-15(FAM) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607156(CHEMBL5219410)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607164(CHEMBL5220605)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human MMP13 using APMA and fTHP-15(FAM) as substrate preincubated for 30 mins followed by substrate addition by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50607147(CHEMBL5220661)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of MMP-2 (unknown origin) using fTHP-15(FAM) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed