Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50019945
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50624895(CHEMBL5394677)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of CSF1R (unknown origin) using poly (4:1 Glu, Tyr) peptide as substrate incubated for 60 mins in presence of ATP by ADP-Glo luminescence ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of CSF1R (unknown origin) using poly (4:1 Glu, Tyr) peptide as substrate incubated for 60 mins in presence of ATP by ADP-Glo luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50: 117nMAssay Description:Inhibition of FLT3 (unknown origin) using TK as substrate incubated for 50 mins in presence of ATP by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50624895(CHEMBL5394677)
Affinity DataIC50: 197nMAssay Description:Inhibition of PDGFR beta (unknown origin) using TK as substrate incubated for 50 mins in presence of ATP by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50624895(CHEMBL5394677)
Affinity DataIC50: 258nMAssay Description:Inhibition of PDGFR alpha (unknown origin) using TK as substrate incubated for 50 mins in presence of ATP by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50: 351nMAssay Description:Inhibition of c-KIT (unknown origin) using TK as substrate incubated for 50 mins in presence of ATP by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50: 359nMAssay Description:Inhibition of PDGFR beta (unknown origin) using TK as substrate incubated for 50 mins in presence of ATP by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of PDGFR alpha (unknown origin) using TK as substrate incubated for 50 mins in presence of ATP by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50624895(CHEMBL5394677)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of FLT3 (unknown origin) using TK as substrate incubated for 50 mins in presence of ATP by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50624895(CHEMBL5394677)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of c-KIT (unknown origin) using TK as substrate incubated for 50 mins in presence of ATP by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed