Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50019805
TargetAurora kinase A(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM209858(Danusertib | N-[5-[(2R)-2-methoxy-2-phenylacetyl]-...)
Affinity DataIC50: 13nMAssay Description:Inhibition of aurora A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50623156(CHEMBL5400975)
Affinity DataIC50: 60nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAurora kinase C(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM209858(Danusertib | N-[5-[(2R)-2-methoxy-2-phenylacetyl]-...)
Affinity DataIC50: 61nMAssay Description:Inhibition of aurora C (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAurora kinase B(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM209858(Danusertib | N-[5-[(2R)-2-methoxy-2-phenylacetyl]-...)
Affinity DataIC50: 79nMAssay Description:Inhibition of aurora B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50623157(CHEMBL5416040)
Affinity DataIC50: 220nMAssay Description:Inhibition of VEGFR-2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Chengdu University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50548084(CHEMBL4786003)
Affinity DataIC50: 4.18E+3nMAssay Description:Inhibition of EGFR (unknown origin) in the presence of ATP by Kinase-Glo Plus luminescence kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed