Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50018126
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 0.0580nMAssay Description:Inhibition of EGFR d746-750/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405287(CHEMBL5290583)
Affinity DataIC50: 0.220nMAssay Description:Inhibition of EGFR d746-750/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405281(CHEMBL5287438)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of EGFR d746-750/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405285(CHEMBL5269317)
Affinity DataIC50: 0.470nMAssay Description:Inhibition of EGFR d746-750/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405288(CHEMBL5286636)
Affinity DataIC50: 0.540nMAssay Description:Inhibition of EGFR d746-750/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405282(CHEMBL5274514)
Affinity DataIC50: 0.550nMAssay Description:Inhibition of EGFR d746-750/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405289(CHEMBL5273197)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of EGFR d746-750/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405286(CHEMBL5289304)
Affinity DataIC50: 0.650nMAssay Description:Inhibition of EGFR d746-750/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405281(CHEMBL5287438)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405290(CHEMBL5266919)
Affinity DataIC50: 3nMAssay Description:Inhibition of EGFR d746-750/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405282(CHEMBL5274514)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405287(CHEMBL5290583)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405283(CHEMBL5286055)
Affinity DataIC50: 7nMAssay Description:Inhibition of EGFR d746-750/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405285(CHEMBL5269317)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405286(CHEMBL5289304)
Affinity DataIC50: 10nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405288(CHEMBL5286636)
Affinity DataIC50: 11nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405289(CHEMBL5273197)
Affinity DataIC50: 13nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405284(CHEMBL5272747)
Affinity DataIC50: 13nMAssay Description:Inhibition of EGFR d746-750/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405283(CHEMBL5286055)
Affinity DataIC50: 20nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405284(CHEMBL5272747)
Affinity DataIC50: 25nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405290(CHEMBL5266919)
Affinity DataIC50: 26nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405281(CHEMBL5287438)
Affinity DataIC50: 40nMAssay Description:Inhibition of EGFR d746-750/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 49nMAssay Description:Inhibition of EGFR d746-750/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405282(CHEMBL5274514)
Affinity DataIC50: 55nMAssay Description:Inhibition of EGFR d746-750/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405283(CHEMBL5286055)
Affinity DataIC50: 87nMAssay Description:Inhibition of EGFR d746-750/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405284(CHEMBL5272747)
Affinity DataIC50: 100nMAssay Description:Inhibition of EGFR d746-750/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405285(CHEMBL5269317)
Affinity DataIC50: 100nMAssay Description:Inhibition of EGFR d746-750/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405286(CHEMBL5289304)
Affinity DataIC50: 100nMAssay Description:Inhibition of EGFR d746-750/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405287(CHEMBL5290583)
Affinity DataIC50: 100nMAssay Description:Inhibition of EGFR d746-750/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405288(CHEMBL5286636)
Affinity DataIC50: 100nMAssay Description:Inhibition of EGFR d746-750/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405289(CHEMBL5273197)
Affinity DataIC50: 100nMAssay Description:Inhibition of EGFR d746-750/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
China State Institute of Pharmaceutical Industry Co.

Curated by ChEMBL
LigandPNGBDBM50405290(CHEMBL5266919)
Affinity DataIC50: 100nMAssay Description:Inhibition of EGFR d746-750/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed