Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50019658
TargetG-protein coupled bile acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621434(CHEMBL390853)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50300199(6alpha-ethyl-23(S)-methyl-cholic acid | CHEMBL5676...)
Affinity DataEC50:  586nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621446(CHEMBL5398966)
Affinity DataEC50:  3.40nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621445(CHEMBL5422904)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621444(CHEMBL5394421)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621443(CHEMBL5415272)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621442(CHEMBL5439914)
Affinity DataEC50:  2.70nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621441(CHEMBL5413666)
Affinity DataEC50:  3.70nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621440(CHEMBL5395284)
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621439(CHEMBL5437749)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621438(CHEMBL5414305)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621437(CHEMBL5427760)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621436(CHEMBL5432337)
Affinity DataEC50:  4.30nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621435(CHEMBL5483060)
Affinity DataEC50:  6nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621434(CHEMBL390853)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50300199(6alpha-ethyl-23(S)-methyl-cholic acid | CHEMBL5676...)
Affinity DataEC50:  2.42E+3nMAssay Description:Agonist activity at human TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetG-protein coupled bile acid receptor 1(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621433(CHEMBL5399395)
Affinity DataEC50:  11nMAssay Description:Agonist activity at mouse TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621433(CHEMBL5399395)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621435(CHEMBL5483060)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621436(CHEMBL5432337)
Affinity DataEC50:  4.5nMAssay Description:Agonist activity at human TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621437(CHEMBL5427760)
Affinity DataEC50:  2.5nMAssay Description:Agonist activity at human TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621438(CHEMBL5414305)
Affinity DataEC50:  2.80nMAssay Description:Agonist activity at human TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621439(CHEMBL5437749)
Affinity DataEC50:  2.80nMAssay Description:Agonist activity at human TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621440(CHEMBL5395284)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at human TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621441(CHEMBL5413666)
Affinity DataEC50:  6.10nMAssay Description:Agonist activity at human TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621442(CHEMBL5439914)
Affinity DataEC50:  4.90nMAssay Description:Agonist activity at human TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621443(CHEMBL5415272)
Affinity DataEC50:  3.70nMAssay Description:Agonist activity at human TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621444(CHEMBL5394421)
Affinity DataEC50:  3.60nMAssay Description:Agonist activity at human TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621445(CHEMBL5422904)
Affinity DataEC50:  3.80nMAssay Description:Agonist activity at human TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621446(CHEMBL5398966)
Affinity DataEC50:  49nMAssay Description:Agonist activity at human TGR5 expressed in human HEK293 cells co-expressing CRE-driven luciferase reporter gene assessed as luciferase activity incu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621447(CHEMBL5411114)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of mouse serum DPP4 assessed as cleavage of substrate by measuring AMC release using Gly-Pro-AMC as substrate by fluorescence based microp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621434(CHEMBL390853)
Affinity DataIC50: 10nMAssay Description:Inhibition of mouse serum DPP4 assessed as cleavage of substrate by measuring AMC release using Gly-Pro-AMC as substrate by fluorescence based microp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621446(CHEMBL5398966)
Affinity DataIC50: 22nMAssay Description:Inhibition of mouse serum DPP4 assessed as cleavage of substrate by measuring AMC release using Gly-Pro-AMC as substrate by fluorescence based microp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621439(CHEMBL5437749)
Affinity DataIC50: 55nMAssay Description:Inhibition of mouse serum DPP4 assessed as cleavage of substrate by measuring AMC release using Gly-Pro-AMC as substrate by fluorescence based microp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621437(CHEMBL5427760)
Affinity DataIC50: 58nMAssay Description:Inhibition of mouse serum DPP4 assessed as cleavage of substrate by measuring AMC release using Gly-Pro-AMC as substrate by fluorescence based microp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621438(CHEMBL5414305)
Affinity DataIC50: 60nMAssay Description:Inhibition of mouse serum DPP4 assessed as cleavage of substrate by measuring AMC release using Gly-Pro-AMC as substrate by fluorescence based microp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621440(CHEMBL5395284)
Affinity DataIC50: 65nMAssay Description:Inhibition of mouse serum DPP4 assessed as cleavage of substrate by measuring AMC release using Gly-Pro-AMC as substrate by fluorescence based microp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621444(CHEMBL5394421)
Affinity DataIC50: 103nMAssay Description:Inhibition of mouse serum DPP4 assessed as cleavage of substrate by measuring AMC release using Gly-Pro-AMC as substrate by fluorescence based microp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621445(CHEMBL5422904)
Affinity DataIC50: 104nMAssay Description:Inhibition of mouse serum DPP4 assessed as cleavage of substrate by measuring AMC release using Gly-Pro-AMC as substrate by fluorescence based microp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621443(CHEMBL5415272)
Affinity DataIC50: 112nMAssay Description:Inhibition of mouse serum DPP4 assessed as cleavage of substrate by measuring AMC release using Gly-Pro-AMC as substrate by fluorescence based microp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621441(CHEMBL5413666)
Affinity DataIC50: 113nMAssay Description:Inhibition of mouse serum DPP4 assessed as cleavage of substrate by measuring AMC release using Gly-Pro-AMC as substrate by fluorescence based microp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621436(CHEMBL5432337)
Affinity DataIC50: 119nMAssay Description:Inhibition of mouse serum DPP4 assessed as cleavage of substrate by measuring AMC release using Gly-Pro-AMC as substrate by fluorescence based microp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621442(CHEMBL5439914)
Affinity DataIC50: 124nMAssay Description:Inhibition of mouse serum DPP4 assessed as cleavage of substrate by measuring AMC release using Gly-Pro-AMC as substrate by fluorescence based microp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621435(CHEMBL5483060)
Affinity DataIC50: 224nMAssay Description:Inhibition of mouse serum DPP4 assessed as cleavage of substrate by measuring AMC release using Gly-Pro-AMC as substrate by fluorescence based microp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 4(Mouse)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621433(CHEMBL5399395)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mouse serum DPP4 assessed as cleavage of substrate by measuring AMC release using Gly-Pro-AMC as substrate by fluorescence based microp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed