Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50019913
TargetDNA (cytosine-5)-methyltransferase 3-like(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624590(CHEMBL5425605)
Affinity DataIC50: 390nMAssay Description:Inhibition of N-terminal His-tagged human DNMT3A (623 to 912 residues)/N-terminal GST-tagged human DNMT3L (160 to 387 residues) co-expressed in bacul...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 3-like(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624591(CHEMBL5415008)
Affinity DataIC50: 700nMAssay Description:Inhibition of N-terminal His-tagged human DNMT3A (623 to 912 residues)/N-terminal GST-tagged human DNMT3L (160 to 387 residues) co-expressed in bacul...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 3-like(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624589(CHEMBL5414585)
Affinity DataIC50: 750nMAssay Description:Inhibition of N-terminal His-tagged human DNMT3A (623 to 912 residues)/N-terminal GST-tagged human DNMT3L (160 to 387 residues) co-expressed in bacul...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 3-like(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624588(CHEMBL5428173)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of N-terminal His-tagged human DNMT3A (623 to 912 residues)/N-terminal GST-tagged human DNMT3L (160 to 387 residues) co-expressed in bacul...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 3-like(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624592(CHEMBL5404240)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of N-terminal His-tagged human DNMT3A (623 to 912 residues)/N-terminal GST-tagged human DNMT3L (160 to 387 residues) co-expressed in bacul...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 3-like(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50430056(CHEMBL2336409 | SGI-1027)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of N-terminal His-tagged human DNMT3A (623 to 912 residues)/N-terminal GST-tagged human DNMT3L (160 to 387 residues) co-expressed in bacul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624592(CHEMBL5404240)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of N-terminal GST-tagged full-length recombinant human DNMT1 assessed as DNA methylation using pdI-pdC DNA as substrate preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624590(CHEMBL5425605)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of N-terminal GST-tagged full-length recombinant human DNMT1 assessed as DNA methylation using pdI-pdC DNA as substrate preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624588(CHEMBL5428173)
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of N-terminal GST-tagged human G9a expressed in baculovirus infected Sf9 cells using biotinylated histone H3 peptide as substrate preincub...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624588(CHEMBL5428173)
Affinity DataIC50: 1.59E+4nMAssay Description:Inhibition of N-terminal GST-tagged full-length recombinant human DNMT1 assessed as DNA methylation using pdI-pdC DNA as substrate preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624589(CHEMBL5414585)
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of N-terminal GST-tagged full-length recombinant human DNMT1 assessed as DNA methylation using pdI-pdC DNA as substrate preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624591(CHEMBL5415008)
Affinity DataIC50: 5.12E+4nMAssay Description:Inhibition of N-terminal GST-tagged full-length recombinant human DNMT1 assessed as DNA methylation using pdI-pdC DNA as substrate preincubated for 1...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 3-like(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624588(CHEMBL5428173)
Affinity DataIC50: 6.47E+4nMAssay Description:Inhibition of N-terminal His-tagged human DNMT3B (564 to 853 residues)/N-terminal GST-tagged human DNMT3L (160 to 387 residues) co-expressed in bacul...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 3-like(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624594(CHEMBL5406502)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal His-tagged human DNMT3A (623 to 912 residues)/N-terminal GST-tagged human DNMT3L (160 to 387 residues) co-expressed in bacul...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 3-like(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624591(CHEMBL5415008)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal His-tagged human DNMT3B (564 to 853 residues)/N-terminal GST-tagged human DNMT3L (160 to 387 residues) co-expressed in bacul...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 3-like(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624593(CHEMBL5415199)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal His-tagged human DNMT3A (623 to 912 residues)/N-terminal GST-tagged human DNMT3L (160 to 387 residues) co-expressed in bacul...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 3-like(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624590(CHEMBL5425605)
Affinity DataIC50: 1.05E+5nMAssay Description:Inhibition of N-terminal His-tagged human DNMT3B (564 to 853 residues)/N-terminal GST-tagged human DNMT3L (160 to 387 residues) co-expressed in bacul...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 3-like(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624592(CHEMBL5404240)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of N-terminal His-tagged human DNMT3B (564 to 853 residues)/N-terminal GST-tagged human DNMT3L (160 to 387 residues) co-expressed in bacul...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetDNA (cytosine-5)-methyltransferase 3-like(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624589(CHEMBL5414585)
Affinity DataIC50: 2.20E+5nMAssay Description:Inhibition of N-terminal His-tagged human DNMT3B (564 to 853 residues)/N-terminal GST-tagged human DNMT3L (160 to 387 residues) co-expressed in bacul...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624592(CHEMBL5404240)
Affinity DataIC50: 3.08E+5nMAssay Description:Inhibition of N-terminal GST-tagged human G9a expressed in baculovirus infected Sf9 cells using biotinylated histone H3 peptide as substrate preincub...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624589(CHEMBL5414585)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of N-terminal GST-tagged human G9a expressed in baculovirus infected Sf9 cells using biotinylated histone H3 peptide as substrate preincub...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624590(CHEMBL5425605)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of N-terminal GST-tagged human G9a expressed in baculovirus infected Sf9 cells using biotinylated histone H3 peptide as substrate preincub...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50624591(CHEMBL5415008)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of N-terminal GST-tagged human G9a expressed in baculovirus infected Sf9 cells using biotinylated histone H3 peptide as substrate preincub...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed