Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50015798
TargetProstaglandin G/H synthase 2(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589579(CHEMBL5185981)
Affinity DataIC50: 3nMAssay Description:Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production and measured after 24 hrs by enzyme immuno-assay (EIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589578(CHEMBL5180981)
Affinity DataIC50: 5nMAssay Description:Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production and measured after 24 hrs by enzyme immuno-assay (EIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589575(CHEMBL5176255)
Affinity DataIC50: 8nMAssay Description:Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production and measured after 24 hrs by enzyme immuno-assay (EIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589572(CHEMBL5189607)
Affinity DataIC50: 9nMAssay Description:Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production and measured after 24 hrs by enzyme immuno-assay (EIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50430948(CHEMBL2337402)
Affinity DataIC50: 14nMAssay Description:Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production and measured after 24 hrs by enzyme immuno-assay (EIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589573(CHEMBL5171792)
Affinity DataIC50: 16nMAssay Description:Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production and measured after 24 hrs by enzyme immuno-assay (EIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589576(CHEMBL5180584)
Affinity DataIC50: 17nMAssay Description:Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production and measured after 24 hrs by enzyme immuno-assay (EIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50430960(CHEMBL2337400)
Affinity DataIC50: 17nMAssay Description:Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production and measured after 24 hrs by enzyme immuno-assay (EIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589574(CHEMBL5195567)
Affinity DataIC50: 25nMAssay Description:Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production and measured after 24 hrs by enzyme immuno-assay (EIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50430954(CHEMBL2337407 | US9162979, 36-II)
Affinity DataIC50: 27nMAssay Description:Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production and measured after 24 hrs by enzyme immuno-assay (EIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589571(CHEMBL5179625)
Affinity DataIC50: 29nMAssay Description:Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production and measured after 24 hrs by enzyme immuno-assay (EIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 61nMAssay Description:Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production and measured after 24 hrs by enzyme immuno-assay (EIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589577(CHEMBL5202601)
Affinity DataIC50: 74nMAssay Description:Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production and measured after 24 hrs by enzyme immuno-assay (EIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50430947(CHEMBL2337409 | US9162979, 37-II)
Affinity DataIC50: 89nMAssay Description:Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production and measured after 24 hrs by enzyme immuno-assay (EIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589582(CHEMBL5176195)
Affinity DataIC50: 140nMAssay Description:Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production and measured after 24 hrs by enzyme immuno-assay (EIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589580(CHEMBL5185512)
Affinity DataIC50: 320nMAssay Description:Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production and measured after 24 hrs by enzyme immuno-assay (EIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50430952(CHEMBL2337396 | US9162979, 39-II)
Affinity DataIC50: 420nMAssay Description:Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production and measured after 24 hrs by enzyme immuno-assay (EIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589581(CHEMBL5170371)
Affinity DataIC50: 916nMAssay Description:Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production and measured after 24 hrs by enzyme immuno-assay (EIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50430958(CHEMBL2337403)
Affinity DataIC50: 920nMAssay Description:Inhibition of COX2 in LPS-stimulated mouse J774 cells assessed as inhibition of PGE2 production and measured after 24 hrs by enzyme immuno-assay (EIA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 3.84E+3nMAssay Description:Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate preincubated for 15 mins followed substrate addition and assessed as inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589573(CHEMBL5171792)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate preincubated for 15 mins followed substrate addition and assessed as inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50430960(CHEMBL2337400)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate preincubated for 15 mins followed substrate addition and assessed as inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50430948(CHEMBL2337402)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate preincubated for 15 mins followed substrate addition and assessed as inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50430958(CHEMBL2337403)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate preincubated for 15 mins followed substrate addition and assessed as inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50430954(CHEMBL2337407 | US9162979, 36-II)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate preincubated for 15 mins followed substrate addition and assessed as inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50430947(CHEMBL2337409 | US9162979, 37-II)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate preincubated for 15 mins followed substrate addition and assessed as inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50430952(CHEMBL2337396 | US9162979, 39-II)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate preincubated for 15 mins followed substrate addition and assessed as inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589571(CHEMBL5179625)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate preincubated for 15 mins followed substrate addition and assessed as inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589572(CHEMBL5189607)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate preincubated for 15 mins followed substrate addition and assessed as inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589577(CHEMBL5202601)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate preincubated for 15 mins followed substrate addition and assessed as inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589574(CHEMBL5195567)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate preincubated for 15 mins followed substrate addition and assessed as inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589575(CHEMBL5176255)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate preincubated for 15 mins followed substrate addition and assessed as inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589576(CHEMBL5180584)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate preincubated for 15 mins followed substrate addition and assessed as inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589582(CHEMBL5176195)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate preincubated for 15 mins followed substrate addition and assessed as inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589581(CHEMBL5170371)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate preincubated for 15 mins followed substrate addition and assessed as inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589580(CHEMBL5185512)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate preincubated for 15 mins followed substrate addition and assessed as inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589579(CHEMBL5185981)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate preincubated for 15 mins followed substrate addition and assessed as inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50589578(CHEMBL5180981)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate preincubated for 15 mins followed substrate addition and assessed as inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed