Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50016159
TargetL-lactate dehydrogenase A chain(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50592885(CHEMBL5206296)
Affinity DataIC50: 12nMAssay Description:Inhibition of LDHA in human Med1 cells using pyruvate as substrate incubated 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50144744(Sodium Oxamate)
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of LDHA in human Med1 cells using pyruvate as substrate incubated 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM23223(Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of mouse LDHB using sodium pyruvate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM23223(Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of human LDHA using sodium pyruvate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50592886(CHEMBL5199516)
Affinity DataKi:  5.46E+3nMAssay Description:Inhibition of LDHA in human liver using pyruvate as substrate incubated for 3 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50592886(CHEMBL5199516)
Affinity DataKi:  1.51E+4nMAssay Description:Inhibition of LDHB in human heart using pyruvate as substrate incubated for 3 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50144744(Sodium Oxamate)
Affinity DataKi:  1.36E+5nMAssay Description:Inhibition of human LDHA using sodium pyruvate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed