Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50017311
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50570253(CHEMBL4467500)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of froskolin-stimulated cAMP accumulation incubated for 90 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50601131(CHEMBL5193398)
Affinity DataEC50:  61nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of froskolin-stimulated cAMP accumulation incubated for 90 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50601131(CHEMBL5193398)
Affinity DataEC50:  8nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of froskolin-stimulated cAMP accumulation at 50 nM incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50601131(CHEMBL5193398)
Affinity DataEC50:  2.20nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of froskolin-stimulated cAMP accumulation incubated for 90 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50601135(CHEMBL5187703)
Affinity DataEC50:  560nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as enhancement of beta arrestin-2 recruitment incubated for 90 mins by HitH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50601134(CHEMBL5205772)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as enhancement of beta arrestin-2 recruitment incubated for 90 mins by HitH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50601133(CHEMBL5185079)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as enhancement of beta arrestin-2 recruitment incubated for 90 mins by HitH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50601132(CHEMBL5204176)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as enhancement of beta arrestin-2 recruitment incubated for 90 mins by HitH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50601131(CHEMBL5193398)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as enhancement of beta arrestin-2 recruitment incubated for 90 mins by HitH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556532(CHEMBL4753891)
Affinity DataEC50:  63nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as enhancement of beta arrestin-2 recruitment incubated for 90 mins by HitH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataEC50:  560nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as enhancement of beta arrestin-2 recruitment incubated for 90 mins by HitH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50601135(CHEMBL5187703)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of froskolin-stimulated cAMP accumulation incubated for 90 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50601134(CHEMBL5205772)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of froskolin-stimulated cAMP accumulation incubated for 90 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50601133(CHEMBL5185079)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of froskolin-stimulated cAMP accumulation incubated for 90 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50601132(CHEMBL5204176)
Affinity DataEC50:  8nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of froskolin-stimulated cAMP accumulation incubated for 90 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50601131(CHEMBL5193398)
Affinity DataEC50:  73nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of froskolin-stimulated cAMP accumulation incubated for 90 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556532(CHEMBL4753891)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of froskolin-stimulated cAMP accumulation incubated for 90 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataEC50:  9.40nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of froskolin-stimulated cAMP accumulation incubated for 90 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50570253(CHEMBL4467500)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as enhancement of beta arrestin-2 recruitment incubated for 90 mins by HitH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556532(CHEMBL4753891)
Affinity DataKi:  0.790nMAssay Description:Displacement of [3H]-CP55,940 from human CB1R expressed in CHO-K1 cell membranes assessed as inhibition constant incubated for 2 hrs by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50601131(CHEMBL5193398)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]-CP55,940 from human CB2R expressed in CHO-K1 cell membranes assessed as inhibition constant incubated for 2 hrs by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50601132(CHEMBL5204176)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]-CP55,940 from human CB2R expressed in CHO-K1 cell membranes assessed as inhibition constant incubated for 2 hrs by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataKi:  6.60nMAssay Description:Displacement of [3H]-CP55,940 from human CB1R expressed in CHO-K1 cell membranes assessed as inhibition constant incubated for 2 hrs by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50556532(CHEMBL4753891)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]-CP55,940 from human CB2R expressed in CHO-K1 cell membranes assessed as inhibition constant incubated for 2 hrs by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50570253(CHEMBL4467500)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-CP55,940 from human CB2R expressed in CHO-K1 cell membranes assessed as inhibition constant incubated for 2 hrs by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]-CP55,940 from human CB2R expressed in CHO-K1 cell membranes assessed as inhibition constant incubated for 2 hrs by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50601131(CHEMBL5193398)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-CP55,940 from human CB1R expressed in CHO-K1 cell membranes assessed as inhibition constant incubated for 2 hrs by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50601132(CHEMBL5204176)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-CP55,940 from human CB1R expressed in CHO-K1 cell membranes assessed as inhibition constant incubated for 2 hrs by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50570253(CHEMBL4467500)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-CP55,940 from human CB1R expressed in CHO-K1 cell membranes assessed as inhibition constant incubated for 2 hrs by liquid scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed