Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50017306
TargetTumor necrosis factor receptor superfamily member 9(Human)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50601006(CHEMBL5208002)
Affinity DataKd:  8.78E+5nMAssay Description:Binding affinity to human CD137 assessed as dissociation constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTumor necrosis factor receptor superfamily member 9(Human)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50601007(CHEMBL5176354)
Affinity DataKd:  2.37E+3nMAssay Description:Binding affinity to human CD137 assessed as dissociation constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTumor necrosis factor receptor superfamily member 9(Human)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50601008(CHEMBL5202442)
Affinity DataKd:  108nMAssay Description:Binding affinity to human recombinant CD137 by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTumor necrosis factor receptor superfamily member 9(Human)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50601009(CHEMBL5209847)
Affinity DataEC50:  73nMAssay Description:Agonist activity at human CD137 expressed in Jurkat T cells co-expressing response element driven luciferase reporter gene assessed as luminescence m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTumor necrosis factor receptor superfamily member 9(Human)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50601010(CHEMBL5204681)
Affinity DataEC50:  3.5nMAssay Description:Agonist activity at human CD137 expressed in Jurkat T cells co-expressing response element driven luciferase reporter gene assessed as luminescence m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNectin-4(Human)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50601011(CHEMBL5202254)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human Nectin-4 expressed in Jurkat T cells co-expressing response element driven luciferase reporter gene assessed as luminescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNectin-4(Human)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50601012(CHEMBL5193789)
Affinity DataEC50:  0.670nMAssay Description:Agonist activity at human Nectin-4 expressed in Jurkat T cells co-expressing response element driven luciferase reporter gene assessed as luminescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNectin-4(Human)
Bicycle Therapeutics

Curated by ChEMBL
LigandPNGBDBM50601008(CHEMBL5202442)
Affinity DataKd:  2.80nMAssay Description:Binding affinity to human Nectin-4 assessed as dissociation constant using 1:1 Nectin-4/CD137 by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed