Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50015748
TargetApelin receptor(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50589283(CHEMBL5172676)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human APJ receptor expressed in HEK293 cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetApelin receptor(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50589292(CHEMBL5185653)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at human APJ receptor expressed in HEK293 cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetApelin receptor(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50589291(CHEMBL5174457)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at human APJ receptor expressed in HEK293 cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetApelin receptor(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50589290(CHEMBL5181275)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human APJ receptor expressed in HEK293 cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetApelin receptor(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50589289(CHEMBL5173131)
Affinity DataEC50:  0.240nMAssay Description:Agonist activity at human APJ receptor expressed in HEK293 cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetApelin receptor(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50589288(CHEMBL5180344)
Affinity DataEC50:  0.240nMAssay Description:Agonist activity at human APJ receptor expressed in HEK293 cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetApelin receptor(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50589287(CHEMBL5201652)
Affinity DataEC50:  0.280nMAssay Description:Agonist activity at human APJ receptor expressed in HEK293 cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetApelin receptor(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50589286(CHEMBL5192333)
Affinity DataEC50:  8.40nMAssay Description:Agonist activity at human APJ receptor expressed in HEK293 cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetApelin receptor(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50589285(CHEMBL5197766)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human APJ receptor expressed in HEK293 cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetApelin receptor(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50589284(CHEMBL5190325)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human APJ receptor expressed in HEK293 cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetApelin receptor(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50014619(CHEMBL3184840)
Affinity DataKd:  0.5nMAssay Description:Binding affinity towards human APJ receptor expressed in HEK293 cell membranes and measured by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetApelin receptor(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50589282(CHEMBL5208913)
Affinity DataEC50: >150nMAssay Description:Agonist activity at human APJ receptor expressed in HEK293 cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetApelin receptor(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50589281(CHEMBL5208554)
Affinity DataEC50:  35nMAssay Description:Agonist activity at human APJ receptor expressed in HEK293 cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetApelin receptor(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50589280(CHEMBL5207156)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human APJ receptor expressed in HEK293 cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetApelin receptor(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50589279(CHEMBL5178186)
Affinity DataEC50:  62nMAssay Description:Agonist activity at human APJ receptor expressed in HEK293 cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetApelin receptor(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50589278(CHEMBL5189404)
Affinity DataEC50: >75nMAssay Description:Agonist activity at human APJ receptor expressed in HEK293 cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetApelin receptor(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50589277(CHEMBL5174935)
Affinity DataEC50: >75nMAssay Description:Agonist activity at human APJ receptor expressed in HEK293 cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetApelin receptor(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50589276(CHEMBL5209078)
Affinity DataEC50:  38nMAssay Description:Agonist activity at human APJ receptor expressed in HEK293 cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetApelin receptor(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50577744(CHEMBL4851693)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human APJ receptor expressed in HEK293 cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetApelin receptor(Human)
Bristol-Myers Squibb Research & Early Development

Curated by ChEMBL
LigandPNGBDBM50014619(CHEMBL3184840)
Affinity DataEC50:  0.0500nMAssay Description:Agonist activity at human APJ receptor expressed in HEK293 cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed