Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50016111
TargetSigma non-opioid intracellular receptor 1(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50592423(CHEMBL4434865)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]-(+)-pentazocine from human sigma1 receptor measured after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50592424(CHEMBL4567314)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-(+)-pentazocine from human sigma1 receptor measured after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50592426(CHEMBL4547253)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-(+)-pentazocine from human sigma1 receptor measured after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50592427(CHEMBL4444356)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]-(+)-pentazocine from human sigma1 receptor measured after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50064947(N-(1-Benzyl-piperidin-4-yl)-2-phenyl-acetamide | C...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50592424(CHEMBL4567314)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]methyl-spiperone from recombinant human D4.4 receptor measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50592426(CHEMBL4547253)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]methyl-spiperone from recombinant human D4.4 receptor measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50059227(1-Benzyl-4-(5-phenyl-1H-pyrazol-3-yl)-piperidine |...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]spiperone from recombinant human D4 receptor stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50592425(CHEMBL4435399)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]methyl-spiperone from recombinant human D4.4 receptor measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50592425(CHEMBL4435399)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-(+)-pentazocine from human sigma1 receptor measured after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50592427(CHEMBL4444356)
Affinity DataKi:  144nMAssay Description:Displacement of [3H]methyl-spiperone from recombinant human D4.4 receptor measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetD(4) dopamine receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50592423(CHEMBL4434865)
Affinity DataKi:  260nMAssay Description:Displacement of [3H]methyl-spiperone from recombinant human D4.4 receptor measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50592423(CHEMBL4434865)
Affinity DataKi:  4.60E+3nMAssay Description:Displacement of [3H]dofetilide from recombinant human ERG stably expressed in HEK293 cell membranes measured after 60 mins by scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50592423(CHEMBL4434865)
Affinity DataKi:  6.30E+3nMAssay Description:Displacement of [3H]methyl-spiperone from recombinant human D2S receptor measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
Bioprojet-Biotech

Curated by ChEMBL
LigandPNGBDBM50592423(CHEMBL4434865)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]methyl-spiperone from recombinant human D3 receptor measured after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed