Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50019482
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50559076(CHEMBL4743159)
Affinity DataIC50: 900nMAssay Description:Inhibition of human His-tagged tyrosinase CD expressed in HEK293 cells assessed as inhibition of melanin production using L-DOPA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50619608(CHEMBL5436579)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50559076(CHEMBL4743159)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50120828(CHEMBL590969)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM49898(SMR000277244 | 4-[2-(pyrimidin-2-ylamino)-1,3-thia...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50619611(CHEMBL5414108)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50619606(CHEMBL5409608)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50619610(CHEMBL5416304)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50559092(CHEMBL4757374)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50559089(CHEMBL4782537)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50559093(CHEMBL4763438)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50619609(CHEMBL5413687)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50619607(CHEMBL5410003)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50248158(N-butylresorcinol | CHEMBL450195 | US8993596, 4-Bu...)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of human His-tagged tyrosinase CD expressed in HEK293 cells assessed as inhibition of melanin production using L-DOPA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM26190(CHEMBL537 | benzene-1,4-diol | Hydroquinone, HQ | ...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human His-tagged tyrosinase CD expressed in HEK293 cells assessed as inhibition of melanin production using L-DOPA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50619616(CHEMBL5430655)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM49724(4-[2-(pyrimidin-2-ylamino)-1,3-thiazol-4-yl]phenol...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50248158(N-butylresorcinol | CHEMBL450195 | US8993596, 4-Bu...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50619615(CHEMBL5440495)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50619605(CHEMBL5435329)
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50619612(CHEMBL5410488)
Affinity DataIC50: 9.30E+4nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM240731(US9422261, 4-(1- phenylethyl) benzene-1,3- diol)
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50619613(CHEMBL5417995)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50619614(CHEMBL5414956)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50031467(Kojic Acid | CHEMBL287556 | 5-HYDROXY-2-(HYDROXYME...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of human His-tagged tyrosinase CD expressed in HEK293 cells assessed as inhibition of melanin production using L-DOPA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50619604(CHEMBL5432134)
Affinity DataIC50: 7.00E+5nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50619602(CHEMBL5400210)
Affinity DataIC50: 7.00E+5nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50619603(CHEMBL5440042)
Affinity DataIC50: 7.00E+5nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50619619(CHEMBL5412774)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50219502(4-hydroxyphenyl beta-D-glucopyranoside | hydroquin...)
Affinity DataIC50: 4.00E+6nMAssay Description:Inhibition of human His-tagged tyrosinase CD expressed in HEK293 cells assessed as inhibition of melanin production using L-DOPA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50619620(CHEMBL1086681 | (-)-Rhododendrol)
Affinity DataIC50: 1.20E+6nMAssay Description:Inhibition of human His-tagged tyrosinase CD expressed in HEK293 cells assessed as inhibition of melanin production using L-DOPA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50619618(CHEMBL5435436)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50619617(CHEMBL5415814)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate incubated for 10 to 20 mins by MBTH dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50559076(CHEMBL4743159)
Affinity DataKi:  250nMAssay Description:Binding affinity to human His-tagged tyrosinase CD expressed in HEK293 cells assessed as inhibition constant using L-DOPA as substrate by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50248158(N-butylresorcinol | CHEMBL450195 | US8993596, 4-Bu...)
Affinity DataKi:  9.00E+3nMAssay Description:Binding affinity to human His-tagged tyrosinase CD expressed in HEK293 cells assessed as inhibition constant using L-DOPA as substrate by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM240731(US9422261, 4-(1- phenylethyl) benzene-1,3- diol)
Affinity DataKi:  2.40E+4nMAssay Description:Binding affinity to human His-tagged tyrosinase CD expressed in HEK293 cells assessed as inhibition constant using L-DOPA as substrate by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetTyrosinase(Human)
King Saud University

Curated by ChEMBL
LigandPNGBDBM50292636(4-hexyl resorcinol | CHEMBL443605 | ACRISORCIN)
Affinity DataKi:  3.90E+4nMAssay Description:Binding affinity to human His-tagged tyrosinase CD expressed in HEK293 cells assessed as inhibition constant using L-DOPA as substrate by HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed