Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50017994
TargetReceptor tyrosine-protein kinase erbB-2(Human)
University of Nimes

Curated by ChEMBL
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of HER2 (unknown origin) incubated for 1 hr in presence of ATP by Kinase-Glo Plus luminescence kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
University of Nimes

Curated by ChEMBL
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 1 hr in presence of ATP by Kinase-Glo Plus luminescence kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
University of Nimes

Curated by ChEMBL
LigandPNGBDBM50606784(CHEMBL5221067)
Affinity DataIC50: 0.140nMAssay Description:Inhibition of HER2 (unknown origin) incubated for 1 hr in presence of ATP by Kinase-Glo Plus luminescence kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
University of Nimes

Curated by ChEMBL
LigandPNGBDBM50606784(CHEMBL5221067)
Affinity DataIC50: 0.470nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 1 hr in presence of ATP by Kinase-Glo Plus luminescence kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
University of Nimes

Curated by ChEMBL
LigandPNGBDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 1 hr in presence of ATP by Kinase-Glo Plus luminescence kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTGF-beta receptor type-1(Human)
University of Nimes

Curated by ChEMBL
LigandPNGBDBM50606782(CHEMBL5218580)
Affinity DataIC50: 87nMAssay Description:Inhibition of human TGF-beta-R1 using TMB substrate incubated for 2.5 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
University of Nimes

Curated by ChEMBL
LigandPNGBDBM50606783(CHEMBL5219198)
Affinity DataIC50: 87nMAssay Description:Inhibition of human TGF-beta-R1 using TMB substrate incubated for 2.5 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
University of Nimes

Curated by ChEMBL
LigandPNGBDBM50606781(CHEMBL5220468)
Affinity DataIC50: 87nMAssay Description:Inhibition of human TGF-beta-R1 using TMB substrate incubated for 2.5 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
University of Nimes

Curated by ChEMBL
LigandPNGBDBM50606781(CHEMBL5220468)
Affinity DataIC50: 90nMAssay Description:Inhibition of human TGF-beta-R1 using TMB substrate incubated for 2.5 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
University of Nimes

Curated by ChEMBL
LigandPNGBDBM50015640(LY-2157299 | GALUNISERTIB)
Affinity DataIC50: 170nMAssay Description:Inhibition of human TGF-beta-R1 using TMB substrate incubated for 2.5 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed