Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50017993
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50606777(CHEMBL5218585)
Affinity DataEC50:  270nMAssay Description:Inhibition of human recombinant IDO1 in human HeLa cells incubated for 48 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50606776(CHEMBL5218729)
Affinity DataEC50:  1.41E+3nMAssay Description:Inhibition of IDO1 in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)
Affinity DataIC50: 0.120nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50285416(CHEMBL4161733)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of IDO1 in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50587578(CHEMBL5091825)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of IDO1 in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50606773(CHEMBL5220107)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of TDO in human BT-549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50606773(CHEMBL5220107)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of IDO1 in human BT-549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50556074(CHEMBL4787695)
Affinity DataIC50: 4nMAssay Description:Inhibition of TDO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50556074(CHEMBL4787695)
Affinity DataIC50: 5nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50606771(CHEMBL5218853)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of recombinant N-terminal His tagged IDO1 (unknown origin) expressed in Escherichia coli incubated for 1.5 hrs by FULOstar OMEGA plate rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50126143(Epacadostat | INCB-024360)
Affinity DataIC50: 10nMAssay Description:Inhibition of human IDO1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50126143(Epacadostat | INCB-024360)
Affinity DataIC50: 13nMAssay Description:Inhibition of IDO1 in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50556061(CHEMBL4756155)
Affinity DataIC50: 13nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50556061(CHEMBL4756155)
Affinity DataIC50: 14nMAssay Description:Inhibition of TDO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50606771(CHEMBL5218853)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant C-terminal His tagged TDO (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50606772(CHEMBL5219853)
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant N-terminal His tagged IDO1 (unknown origin) expressed in Escherichia coli incubated for 1.5 hrs by FULOstar OMEGA plate rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50556074(CHEMBL4787695)
Affinity DataIC50: 59nMAssay Description:Inhibition of TDO in human A-172 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50556044(CHEMBL4300931)
Affinity DataIC50: 70nMAssay Description:Inhibition of TDO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50126143(Epacadostat | INCB-024360)
Affinity DataIC50: 73nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetTryptophan 2,3-dioxygenase(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50606772(CHEMBL5219853)
Affinity DataIC50: 78nMAssay Description:Inhibition of recombinant C-terminal His tagged TDO (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50606776(CHEMBL5218729)
Affinity DataIC50: 84nMAssay Description:Inhibition of human N-terminal His tagged recombinant IDO1 (5 to 403 residues) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50556074(CHEMBL4787695)
Affinity DataIC50: 98nMAssay Description:Inhibition of IDO1 in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50556044(CHEMBL4300931)
Affinity DataIC50: 100nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50606777(CHEMBL5218585)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant IDO1More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50606779(CHEMBL5220149)
Affinity DataIC50: 460nMAssay Description:Inhibition of HDAC1 (unknown origin) using trypsin as substrate preincubated for 15 mins followed by substrate addition measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50606778(CHEMBL5219214)
Affinity DataIC50: 510nMAssay Description:Inhibition of IDO1 (unknown origin) using L-tryptophan as substrate incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50606779(CHEMBL5220149)
Affinity DataIC50: 730nMAssay Description:Inhibition of IDO1 (unknown origin) using L-tryptophan as substrate incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50550891(CHEMBL4763910)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50550891(CHEMBL4763910)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of TDO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50606780(CHEMBL328673)
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibition of IDO1 (unknown origin) using L-tryptophan as substrate incubated for 10 mins relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50562506(CHEMBL4791168)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human TDO by UV based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50550888(CHEMBL4749277)
Affinity DataIC50: 3.18E+3nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50550888(CHEMBL4749277)
Affinity DataIC50: 7.12E+3nMAssay Description:Inhibition of TDO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50550852(CHEMBL4790494)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50550852(CHEMBL4790494)
Affinity DataIC50: 8.48E+3nMAssay Description:Inhibition of TDO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50606775(CHEMBL5218772)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of TDO in human BT-549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50606775(CHEMBL5218772)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of IDO1 in human BT-549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50606769(CHEMBL5219208)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50606774(CHEMBL5220064)
Affinity DataIC50: 2.06E+4nMAssay Description:Inhibition of TDO in human BT-549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50606774(CHEMBL5220064)
Affinity DataIC50: 2.06E+4nMAssay Description:Inhibition of IDO1 in human BT-549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50550848(CHEMBL4749687)
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of TDO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50550848(CHEMBL4749687)
Affinity DataIC50: 3.56E+4nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50606773(CHEMBL5220107)
Affinity DataIC50: 3.77E+4nMAssay Description:Inhibition of IDO1 in human A-172 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50606773(CHEMBL5220107)
Affinity DataIC50: 4.73E+4nMAssay Description:Inhibition of IDO1 in human SK-OV-3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50562506(CHEMBL4791168)
Affinity DataIC50: 9.45E+4nMAssay Description:Inhibition of human recombinant N-terminal His tagged IDO1 expressed in Escherichia coli using L-Trp as substrate by measuring amount of N-formylkynu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50606770(CHEMBL5220249)
Affinity DataIC50: 2.27E+5nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM370555(US10233190, Example 1488 | (1R,4r)-4-((R)-2-((S)-6...)
Affinity DataKi:  28nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
National Clinical Research Center For Geriatrics

Curated by ChEMBL
LigandPNGBDBM50207089(D-1-Methyltryptophan | D-1MT | Indoximod)
Affinity DataKi:  3.50E+4nMAssay Description:Binding affinity to IDO1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed