Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50018111
TargetCannabinoid receptor 2(Human)
University of Otago Dunedin

Curated by ChEMBL
LigandPNGBDBM50404173(CHEMBL5266788)
Affinity DataKi:  0.0750nMAssay Description:Antagonist activity at human CB2R assessed as beta arrestin-2 recruitment by measuring inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 2(Human)
University of Otago Dunedin

Curated by ChEMBL
LigandPNGBDBM50404172(CHEMBL5273987)
Affinity DataKi:  0.630nMAssay Description:Binding affinity to wild type human CB2R expressed in HEK293 cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
University of Otago Dunedin

Curated by ChEMBL
LigandPNGBDBM21279(N-(piperidin-1-yl)-1-(2,4-dichlorophenyl)-5-(4-iod...)
Affinity DataKi:  7.5nMAssay Description:Antagonist activity at rat forebrain CB1R assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
University of Otago Dunedin

Curated by ChEMBL
LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataKi:  12nMAssay Description:Antagonist activity at rat forebrain CB1R assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Human)
University of Otago Dunedin

Curated by ChEMBL
LigandPNGBDBM50404173(CHEMBL5266788)
Affinity DataKi:  13nMAssay Description:Antagonist activity at human CB1R assessed as beta arrestin-2 recruitment by measuring inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
University of Otago Dunedin

Curated by ChEMBL
LigandPNGBDBM50110953(4-Methyl-1-pentyl-5-phenyl-1H-pyrazole-3-carboxyli...)
Affinity DataKi:  23nMAssay Description:Binding affinity to rat CB1R assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Otago Dunedin

Curated by ChEMBL
LigandPNGBDBM50399157(CHEMBL2179724)
Affinity DataKi:  23nMAssay Description:Antagonist activity at human CB2R expressed in CHO cells assessed as inhibition of forskolin stimulated cyclic AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 2(Mouse)
University of Otago Dunedin

Curated by ChEMBL
LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataKi:  1.64E+3nMAssay Description:Antagonist activity at mouse spleen CB2R assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
University of Otago Dunedin

Curated by ChEMBL
LigandPNGBDBM21279(N-(piperidin-1-yl)-1-(2,4-dichlorophenyl)-5-(4-iod...)
Affinity DataKi:  2.29E+3nMAssay Description:Antagonist activity at rat forebrain CB1R assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCannabinoid receptor 1(Rat)
University of Otago Dunedin

Curated by ChEMBL
LigandPNGBDBM50399157(CHEMBL2179724)
Affinity DataKi: >1.00E+4nMAssay Description:Antagonist activity at rat CB1R expressed in CHO cells assessed as inhibition of forskolin stimulated cyclic AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed