Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50016102
TargetStimulator of interferon genes protein(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592350(CHEMBL5187622)
Affinity DataEC50:  3.28E+4nMAssay Description:Agonist activity at STING in mouse RAW-Lucia ISG cells assessed as ISG activation incubated for 24 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50562112(CHEMBL4743888)
Affinity DataEC50:  185nMAssay Description:Agonist activity at human STINGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509050(CHEMBL4438309)
Affinity DataEC50: <1nMAssay Description:Agonist activity at STING in human THP1-Dual cells assessed as ISG activation incubated for 24 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592350(CHEMBL5187622)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at STING in human THP1-Dual cells assessed as ISG activation incubated for 24 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592351(CHEMBL5188508)
Affinity DataEC50:  5.82E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells assessed as ISG activation incubated for 24 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592352(CHEMBL5189647)
Affinity DataEC50:  1.56E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells assessed as ISG activation incubated for 24 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592353(CHEMBL5174477)
Affinity DataEC50:  280nMAssay Description:Agonist activity at STING in human THP1-Dual cells assessed as ISG activation incubated for 24 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592354(CHEMBL5195931)
Affinity DataEC50:  1.86E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells assessed as ISG activation incubated for 24 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509050(CHEMBL4438309)
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity at STING in mouse RAW-Lucia ISG cells assessed as ISG activation incubated for 24 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592349(CHEMBL5178162)
Affinity DataEC50:  2.49E+3nMAssay Description:Agonist activity at wild type human STING in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592351(CHEMBL5188508)
Affinity DataEC50:  6.37E+4nMAssay Description:Agonist activity at STING in mouse RAW-Lucia ISG cells assessed as ISG activation incubated for 24 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592352(CHEMBL5189647)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING in mouse RAW-Lucia ISG cells assessed as ISG activation incubated for 24 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592353(CHEMBL5174477)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING in mouse RAW-Lucia ISG cells assessed as ISG activation incubated for 24 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592354(CHEMBL5195931)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING in mouse RAW-Lucia ISG cells assessed as ISG activation incubated for 24 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509050(CHEMBL4438309)
Affinity DataEC50:  1.30E+5nMAssay Description:Agonist activity at human wild type STINGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509049(CHEMBL4440744)
Affinity DataEC50:  3.10E+3nMAssay Description:Agonist activity at human wild type STINGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592347(CHEMBL5175901)
Affinity DataEC50:  287nMAssay Description:Agonist activity at human wild type STINGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50566270(CHEMBL4876319)
Affinity DataEC50:  240nMAssay Description:Agonist activity at human wild type STINGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509049(CHEMBL4440744)
Affinity DataKd:  1.60nMAssay Description:Binding affinity to human wild type STING assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50506263(CHEMBL4465054 | US11401295, Compound 2',3'-cGAMP)
Affinity DataKd:  3.79E+3nMAssay Description:Agonist activity at wild type human STING C-terminal domain (139 to 379 residues) assessed as dissociation constant by isothermal titration calorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509401(CHEMBL4449584)
Affinity DataKd:  1.04E+3nMAssay Description:Agonist activity at wild type human STING C-terminal domain (139 to 379 residues) assessed as dissociation constant by isothermal titration calorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592345(CHEMBL5195199)
Affinity DataEC50:  180nMAssay Description:Agonist activity at STING (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592346(CHEMBL5190773)
Affinity DataEC50:  4.15E+4nMAssay Description:Agonist activity at STING (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50506263(CHEMBL4465054 | US11401295, Compound 2',3'-cGAMP)
Affinity DataEC50:  1.96E+4nMAssay Description:Agonist activity at STING (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509429(CHEBI:71578 | CHEMBL1229884)
Affinity DataEC50:  51nMAssay Description:Agonist activity at STING (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511078(CHEBI:75934 | AS-1404 | ASA-404 | ASA404 | DMXAA |...)
Affinity DataKd:  710nMAssay Description:Binding affinity to mouse STING assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511089(Cridanimod)
Affinity DataKd:  3.50E+3nMAssay Description:Binding affinity to mouse STING assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50436163(CHEMBL1231573)
Affinity DataKd:  1.21E+3nMAssay Description:Agonist activity at wild type human STING C-terminal domain (139 to 379 residues) assessed as dissociation constant by isothermal titration calorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509050(CHEMBL4438309)
Affinity DataEC50:  190nMAssay Description:Agonist activity at human STING HAQ mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM453551(4-(5,6-dimethoxybenzo[b]thiophen-2-yl)-4- oxobutan...)
Affinity DataEC50:  8.30E+3nMAssay Description:Agonist activity at human STING HAQ mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50509050(CHEMBL4438309)
Affinity DataEC50:  186nMAssay Description:Agonist activity at mouse STINGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50566270(CHEMBL4876319)
Affinity DataEC50:  3.95E+4nMAssay Description:Agonist activity at mouse STINGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592348(CHEMBL5185691)
Affinity DataEC50:  2.10E+3nMAssay Description:Agonist activity at STING in human THP-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592347(CHEMBL5175901)
Affinity DataIC50: 379nMAssay Description:Inhibition of human wild type STING by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50511093(CHEMBL4522871)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human wild type STINGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed