Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50015739
TargetP2Y purinoceptor 12(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50589230(CHEMBL5181634)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]-2MesADP from human P2Y12 in HEK cell membrane assessed as inhibition constant incubated for 1 hr by scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50118225(ARL 69931MX | Adenosine triphosphate derivative | ...)
Affinity DataIC50: 0.450nMAssay Description:Inhibition of P2Y12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50298132((4S)4-[({4-[4-(Methoxymethyl)piperidin-1-yl]-6-phe...)
Affinity DataKi:  3.5nMAssay Description:Binding affinity to P2Y12 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50589232(CHEMBL5199350)
Affinity DataKd:  6.5nMAssay Description:Displacement of [3H]PSB-0413 from P2Y12 in human platelets assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50397143(CHEMBL2172140)
Affinity DataKi:  7.70nMAssay Description:Binding affinity to P2Y12 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50589229(CHEMBL5203993)
Affinity DataKi:  9nMAssay Description:Displacement of [33P]-2MeS-ADP from recombinant human P2Y12 transfected in HEK cell membrane assessed as inhibition constant incubated for 1 hr by co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50397205(AR-C126532XX | AZD-6140 | AZD6140 | BRILINTA | TIC...)
Affinity DataIC50: 10nMAssay Description:Inhibition of P2Y12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50100247(CHEMBL3325891)
Affinity DataIC50: 17nMAssay Description:Inhibition of P2Y12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50397204(ELINOGREL)
Affinity DataKi:  23nMAssay Description:Binding affinity to P2Y12 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50268877(Disodium 1-Amino-4-[4-phenylamino-3-sulfophenylami...)
Affinity DataKi:  25nMAssay Description:Binding affinity to P2Y12 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50118242([({[(2R,3S,4R,5R)-5-[6-amino-2-(methylsulfanyl)-9H...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]-2MesADP from recombinant human P2Y12 transfected in HEK cell membrane assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetP2Y purinoceptor 12(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50589231(PRASUGREL | CHEBI:87723 | Prasugrel | LY-640315 | ...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of P2Y12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetP2Y purinoceptor 12(Human)
The University of Sydney

Curated by ChEMBL
LigandPNGBDBM50397662(CLOPIDOGREL)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of P2Y12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed