Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50016907
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598252(CHEMBL5206463)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598249(CHEMBL5193565)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598229(CHEMBL5209435)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598251(CHEMBL5182494)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598254(CHEMBL5169436)
Affinity DataIC50: 10nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598250(CHEMBL5203955)
Affinity DataIC50: 11nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598253(CHEMBL5200075)
Affinity DataIC50: 13nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598230(CHEMBL5198888)
Affinity DataIC50: 14nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598228(CHEMBL5186273)
Affinity DataIC50: 14nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598231(CHEMBL5194645)
Affinity DataIC50: 16nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598246(CHEMBL5174428)
Affinity DataIC50: 20nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598243(CHEMBL5191795)
Affinity DataIC50: 20nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598248(CHEMBL5201005)
Affinity DataIC50: 22nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598245(CHEMBL5177094)
Affinity DataIC50: 22nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598242(CHEMBL5173982)
Affinity DataIC50: 23nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598244(CHEMBL5175230)
Affinity DataIC50: 26nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598239(CHEMBL5182196)
Affinity DataIC50: 27nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598238(CHEMBL5198288)
Affinity DataIC50: 27nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598236(CHEMBL5179920)
Affinity DataIC50: 29nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598234(CHEMBL5171811)
Affinity DataIC50: 29nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598241(CHEMBL5181287)
Affinity DataIC50: 30nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598232(CHEMBL5183905)
Affinity DataIC50: 30nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598237(CHEMBL5186097)
Affinity DataIC50: 31nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598247(CHEMBL5174482)
Affinity DataIC50: 33nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598227(CHEMBL5197464)
Affinity DataIC50: 35nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598240(CHEMBL5208193)
Affinity DataIC50: 38nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598235(CHEMBL5177668)
Affinity DataIC50: 40nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598226(CHEMBL5197071)
Affinity DataIC50: 41nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598233(CHEMBL5191491)
Affinity DataIC50: 43nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM119812(US8691852, 20 | US20240034730, Compound ASLAN003)
Affinity DataIC50: 44nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50598225(CHEMBL5175336)
Affinity DataIC50: 52nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50018011(CHEBI:68540 | HMR-1726 | Aubagio | TERIFLUNOMIDE)
Affinity DataIC50: 408nMAssay Description:Inhibition of human N-terminal SUMO-tagged DHODH expressed in Escherichia coli BL21(DE3) using dihydroorotate substrate by DCIP based microplate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)