Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50016480
TargetSpike glycoprotein(2019-nCoV)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50595278(CHEMBL5205832)
Affinity DataKd:  6.94E+3nMAssay Description:Binding affinity to SARS-CoV-2 spike protein receptor-binding domain assessed as equilibrium dissociation constant by biolayer interferometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetSpike glycoprotein(2019-nCoV)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50595279(CHEMBL5187952)
Affinity DataKd:  7.29E+3nMAssay Description:Binding affinity to SARS-CoV-2 spike protein receptor-binding domain assessed as equilibrium dissociation constant by biolayer interferometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetSpike glycoprotein(2019-nCoV)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50157304(3',5-diallylbiphenyl-2,4'-diol | CHEMBL16901 | cid...)
Affinity DataKd:  2.50E+4nMAssay Description:Binding affinity to SARS-CoV-2 spike protein receptor-binding domain assessed as equilibrium dissociation constant by biolayer interferometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50595278(CHEMBL5205832)
Affinity DataKd:  1.40E+4nMAssay Description:Binding affinity to human ACE2 assessed as equilibrium dissociation constant by biolayer interferometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50595279(CHEMBL5187952)
Affinity DataKd:  1.60E+4nMAssay Description:Binding affinity to human ACE2 assessed as equilibrium dissociation constant by biolayer interferometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAngiotensin-converting enzyme 2(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50157304(3',5-diallylbiphenyl-2,4'-diol | CHEMBL16901 | cid...)
Affinity DataKd:  1.70E+4nMAssay Description:Binding affinity to human ACE2 assessed as equilibrium dissociation constant by biolayer interferometry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMaltase-glucoamylase(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50595275(CHEMBL5202537)
Affinity DataIC50: 1.89E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNPG as substrate preincubated for 15 mins followed by substrate addition and measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMaltase-glucoamylase(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM23406((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...)
Affinity DataIC50: 2.44E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNPG as substrate preincubated for 15 mins followed by substrate addition and measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMaltase-glucoamylase(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50595276(CHEMBL5186121)
Affinity DataIC50: 2.45E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNPG as substrate preincubated for 15 mins followed by substrate addition and measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMaltase-glucoamylase(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50595274(CHEMBL5178321)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNPG as substrate preincubated for 15 mins followed by substrate addition and measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMaltase-glucoamylase(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50595273(CHEMBL5209522)
Affinity DataIC50: 2.58E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNPG as substrate preincubated for 15 mins followed by substrate addition and measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMaltase-glucoamylase(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50595277(CHEMBL5195148)
Affinity DataIC50: 5.29E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNPG as substrate preincubated for 15 mins followed by substrate addition and measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMaltase-glucoamylase(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50595275(CHEMBL5202537)
Affinity DataKi:  2.08E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) assessed as inhibition constant incubated for 15 mins by dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed