Compile Data Set for Download or QSAR
Report error Found 75 Enz. Inhib. hit(s) with all data for entry = 50017893
LigandPNGBDBM50605881(CHEMBL5189787)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605880(CHEMBL5174424)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605877(CHEMBL5176939)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605878(CHEMBL5180133)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605888(CHEMBL5179759)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605879(CHEMBL5176141)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605876(CHEMBL5170797)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605885(CHEMBL5181374)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605874(CHEMBL5207799)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605889(CHEMBL5200752)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605875(CHEMBL5208183)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605882(CHEMBL5202280)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605887(CHEMBL5193778)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605883(CHEMBL5189320)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605868(CHEMBL5186978)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605890(CHEMBL5200451)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605891(CHEMBL5174560)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605894(CHEMBL5176630)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605869(CHEMBL5185502)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605884(CHEMBL5193523)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605893(CHEMBL5208332)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605892(CHEMBL5178153)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCytochrome P450 2C19(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605868(CHEMBL5186978)
Affinity DataIC50: 1.46E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCytochrome P450 2B6(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605868(CHEMBL5186978)
Affinity DataIC50: 2.08E+4nMAssay Description:Inhibition of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605898(CHEMBL5184265)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605897(CHEMBL5206831)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605904(CHEMBL5179688)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605901(CHEMBL5207798)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605900(CHEMBL5200620)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605899(CHEMBL5192467)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605896(CHEMBL5197481)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
LigandPNGBDBM50605895(CHEMBL5195083)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG expressed in CHO cells stably at -80 mV holding potential by automated patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCytochrome P450 2C9(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605868(CHEMBL5186978)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCytochrome P450 2D6(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605868(CHEMBL5186978)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605868(CHEMBL5186978)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCytochrome P450 2C8(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605868(CHEMBL5186978)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCytochrome P450 1A2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605868(CHEMBL5186978)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605870(CHEMBL5196475)
Affinity DataKi:  0.490nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605882(CHEMBL5202280)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605891(CHEMBL5174560)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605874(CHEMBL5207799)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605904(CHEMBL5179688)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605888(CHEMBL5179759)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605868(CHEMBL5186978)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605869(CHEMBL5185502)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM133427(US8846719, 112)
Affinity DataKi:  4.40nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605890(CHEMBL5200451)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605894(CHEMBL5176630)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605885(CHEMBL5181374)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605892(CHEMBL5178153)
Affinity DataKi:  7.30nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
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