Compile Data Set for Download or QSAR
Report error Found 78 Enz. Inhib. hit(s) with all data for entry = 50016285
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50593904(CHEMBL5198209)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 0.460nMAssay Description:Inhibition of CDK7/Cyclin H (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50593907(CHEMBL5178590)
Affinity DataIC50: 0.550nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of CDK9/Cyclin T1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCDK9/Cyclin-T2(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50193104(CHEMBL3905910)
Affinity DataIC50: 0.626nMAssay Description:Inhibition of CDK9/Cyclin T2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50593909(CHEMBL5207372)
Affinity DataIC50: 0.650nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM7533(2,6,9-Trisubstituted purine deriv. 28 | (2R)-2-[[6...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) expressed in baculovirus infected Sf9 cells using histone H1 as substrate incubated for 10 mins in prese...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50593913(CHEMBL5174604)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50593905(CHEMBL5185047)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50593903(CHEMBL5190531)
Affinity DataIC50: 0.820nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50593911(CHEMBL5193922)
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50139171(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK5/p35 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM112464(US8623885, 5)
Affinity DataIC50: 1nMAssay Description:Inhibition of FLT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM12621(2,4-Diamino-5-ketopyrimidine 39 | 5-[(2,3-difluoro...)
Affinity DataIC50: 1nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50593912(CHEMBL5170190)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50553499(CHEMBL4754493)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of CDK7/Cyclin H (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCasein kinase I isoform delta(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50553499(CHEMBL4754493)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of CSNK1D (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50593908(CHEMBL5209261)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM7501(CHEMBL48362 | 4-{[(2Z)-4,6-dihydroxy-7-(1-methylpi...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50593901(CHEMBL5196505)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM7498(CHEMBL51709 | (2Z)-2-benzylidene-4,6-dihydroxy-7-(...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50593906(CHEMBL5193072)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50593924(Avotaciclib | Bey1107 | Cdk1 inhibitor bey1107 | B...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of CDK5/p35 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50593910(CHEMBL5173446)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50553483(CHEMBL4756595 | US20230416221, Compound BAY1251152)
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK9/Cyclin T (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50511932(CHEMBL4589128)
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) in presence of [32P]ATP by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 7(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50593925(CHEMBL5196685)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of CDK7 (unknown origin) incubated for 180 mins by LanthaScreen Eu kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50528817(CHEMBL4462530 | US10717746, Example 14 | US2023041...)
Affinity DataIC50: 4nMAssay Description:Inhibition of CDK9/Cyclin T (unknown origin) in presence of ATP by Kinomescan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50553499(CHEMBL4754493)
Affinity DataIC50: 4nMAssay Description:Inhibition of CDK9/Cyclin T (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM5931(cid_3025986 | CHEMBL296468 | N-(5-{[(5-tert-butyl-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of CDK9/Cyclin T (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50139171(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)
Affinity DataIC50: 4nMAssay Description:Inhibition of CDK9/Cyclin T (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-C(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50459995(CHEMBL4225966 | US11471446, Compound DBA-10)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of CDK8/Cyclin C (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCasein kinase I isoform epsilon(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50553499(CHEMBL4754493)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of CSNK1E (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50553480(CHEMBL4741442)
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK9/Cyclin T1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50511926(CHEMBL4442620)
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK9/Cyclin T1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 2(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50593923(CHEMBL5195030)
Affinity DataIC50: 5nMAssay Description:Inhibition of human full-length recombinant CDK2 (1 to 298 residues) expressed in baculovirus infected Sf21 insect cells in presence of ATP by enzyma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCasein kinase I isoform alpha(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50553499(CHEMBL4754493)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of CSNK1A1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50593922(CHEMBL5199065)
Affinity DataIC50: 6nMAssay Description:Inhibition of CDK9/Cyclin T1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50593899(CHEMBL5176598)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50593914(CHEMBL5192860)
Affinity DataIC50: 7nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-C/Cyclin-dependent kinase 19(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50459995(CHEMBL4225966 | US11471446, Compound DBA-10)
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK19/Cyclin C (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50113281(AT-7519 | US20240293557, Compound AMC-3-098 | US12...)
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK9/Cyclin T (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50511926(CHEMBL4442620)
Affinity DataIC50: 11nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM168383(US9669034, 2 (rac)-4-(4-Fluoro-2-methoxyphenyl)-N-...)
Affinity DataIC50: 13nMAssay Description:Inhibition of His-tagged full-length recombinant human CDK9/Cyclin T1 expressed in insect cells using Biotin-tagged Ttds-YISPLKSPYKISEG peptide as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50363196(CHEMBL1944698)
Affinity DataIC50: 13nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM12611(2-N-(1-methanesulfonylpiperidin-4-yl)-5-[(2-methox...)
Affinity DataIC50: 14nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50593921(CHEMBL5175859)
Affinity DataIC50: 14nMAssay Description:Inhibition of CDK9/Cyclin T1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50593900(CHEMBL5178317)
Affinity DataIC50: 16nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 7(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM50593926(CHEMBL5207274)
Affinity DataIC50: 17nMAssay Description:Inhibition of CDK7 (unknown origin) using 5-FAM-tagged YSPTSPSYSPTSPSYSPTSPSKKKK peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
The People'S Hospital of Xinjiang Uyghur Autonomous Region

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50: 20nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
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