Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50016059
TargetEpidermal growth factor receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50591813(CHEMBL5206715)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of EGFR del19/T790M mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50591813(CHEMBL5206715)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50591813(CHEMBL5206715)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of EGFR del19/T790M/C797S mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50591813(CHEMBL5206715)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of EGFR L858R/T790M/C797S mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of EGFR del19/T790M mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50591813(CHEMBL5206715)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of EGFR del19 mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50591813(CHEMBL5206715)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of EGFR del19/T790M/C797S mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of EGFR L858R/T790M/C797S mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50591813(CHEMBL5206715)
Affinity DataIC50: 10nMAssay Description:Inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 11nMAssay Description:Inhibition of EGFR del19 mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 28nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 75nMAssay Description:Inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)