Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50016451
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50595033(CHEMBL5175996)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of GSK-3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50595037(CHEMBL5186457)
Affinity DataIC50: 3nMAssay Description:Inhibition of GSK-3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50595035(CHEMBL5203304)
Affinity DataIC50: 4nMAssay Description:Inhibition of GSK-3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50267605(3-(benzofuran-3-yl)-4-(5-bromo-1-methyl-1H-indol-3...)
Affinity DataIC50: 7nMAssay Description:Inhibition of GSK-3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50537547(CHEMBL4645337)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant GST-tagged GSK3-beta incubated for 1 hr by Envision plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM2600(3-(1-benzofuran-3-yl)-4-(1-methyl-1H-indol-3-yl)-2...)
Affinity DataIC50: 35nMAssay Description:Inhibition of GSK-3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50595036(CHEMBL5184987)
Affinity DataIC50: 72nMAssay Description:Inhibition of GSK-3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50595039(WUWEIZISU B | CHEBI:4410)
Affinity DataIC50: 73nMAssay Description:Inhibition of human recombinant GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50595038(KADSURANIN | Kadsuranin | CHEBI:5517)
Affinity DataIC50: 81nMAssay Description:Inhibition of human recombinant GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50585162(CHEMBL5074629)
Affinity DataIC50: 130nMAssay Description:Inhibition of GSK-3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50267522(3-Benzofuran-3-yl-4-(6-chloro-5-fluoro-1-methyl-1H...)
Affinity DataIC50: 184nMAssay Description:Inhibition of GSK-3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50595041(CHEMBL5185897)
Affinity DataIC50: 600nMAssay Description:Inhibition of GSK-3beta (unknown origin) using peptide YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate incubated for 5 to 60 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50585161(CHEMBL5087421)
Affinity DataIC50: 764nMAssay Description:Inhibition of GSK-3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50595040(CHEMBL5170269)
Affinity DataIC50: 883nMAssay Description:Inhibition of GSK3-beta (unknown origin) by Kinase-Glo Max assay kitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50595050(CHEMBL5181975)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of GSK-3beta (unknown origin) using biotin-labelled IRS-1 peptide as substrate incubated for 15 mins by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50595049(CHEMBL5183472)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of GSK-3beta (unknown origin) using biotin-labelled IRS-1 peptide as substrate incubated for 15 mins by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50595034(CHEMBL5182770)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of GSK-3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50595046(CHEMBL5184052)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of GSK-3beta (unknown origin) using peptide YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate incubated for 5 to 60 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM7781(4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of GSK-3beta (unknown origin) using GS-1 as substrate incubated for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM7793(2-methyl-4-(1-naphthyl)-1,2,4-thiadiazolidine-3,5-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of GSK-3beta (unknown origin) using GS-1 as substrate incubated for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM7853(2-chloro-1-(4,5-dichlorothiophen-2-yl)ethan-1-one ...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of GSK-3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM7774(4-Ethyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione |...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of GSK-3beta (unknown origin) using GS-1 as substrate incubated for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50595045(CHEMBL5187137)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of GSK-3beta (unknown origin) using peptide YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate incubated for 5 to 60 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50595048(CHEMBL5174091)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of GSK-3beta (unknown origin) using biotin-labelled IRS-1 peptide as substrate incubated for 15 mins by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50595044(CHEMBL5197740)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of GSK-3beta (unknown origin) using peptide YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate incubated for 5 to 60 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM7867(1-(5-bromothiophen-2-yl)-2-chloroethan-1-one | Chl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GSK-3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50595043(CHEMBL5170348)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of GSK-3beta (unknown origin) using peptide YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate incubated for 5 to 60 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50595042(CHEMBL5195696)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of GSK-3beta (unknown origin) using peptide YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate incubated for 5 to 60 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50595047(CHEMBL5197823)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of GSK-3beta (unknown origin) using biotin-labelled IRS-1 peptide as substrate incubated for 15 mins by ELISA based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM7794(2,4-diethyl-3-thioxo-1,2,4-thiadiazolidin-5-one | ...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of GSK-3beta (unknown origin) using GS-1 as substrate incubated for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM7775(2,4-Diethyl-1,2,4-thiadiazolidine-3,5-dione | Thia...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of GSK-3beta (unknown origin) using GS-1 as substrate incubated for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM7858(2-chloro-1-(thiophen-2-yl)ethan-1-one | Chlorometh...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of GSK-3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50508432(6-(Methylsulfinyl)Hexyl Isothiocyanate | CHEMBL573...)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of GSK-3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProtein kinase C zeta type(Rat)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM7781(4-Benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat brain PKC using peptide PANKTPPKSPGEPAK as substrate incubated for 20 mins in presence of phosphatidyl serineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM7860(2-chloro-1-(5-methylthiophen-2-yl)ethan-1-one | Ch...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GSK-3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50487756(CHEBI:17965 | Isoorientin)
Affinity DataIC50: 1.85E+5nMAssay Description:Inhibition of GSK-3beta (unknown origin) using peptide YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate incubated for 5 to 60 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed