Compile Data Set for Download or QSAR
Report error Found 76 Enz. Inhib. hit(s) with all data for entry = 50017751
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604704(CHEMBL5203346)
Affinity DataEC50:  3nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604695(CHEMBL5207893)
Affinity DataEC50:  2.20nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604696(CHEMBL5208566)
Affinity DataEC50:  6.60nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604697(CHEMBL5173113)
Affinity DataEC50:  1.10nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604698(CHEMBL5184413)
Affinity DataEC50:  1.30nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604699(CHEMBL5198894)
Affinity DataEC50:  2.60nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604700(CHEMBL5191391)
Affinity DataEC50:  2.20nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604701(CHEMBL5205039)
Affinity DataEC50:  1.30nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604702(CHEMBL5181826)
Affinity DataEC50:  3.40nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604703(CHEMBL5181850)
Affinity DataEC50:  0.400nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604677(CHEMBL5189071)
Affinity DataEC50:  2.20nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604705(CHEMBL5205357)
Affinity DataEC50:  1.80nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604706(CHEMBL5171948)
Affinity DataEC50:  1.40nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604707(CHEMBL5169445)
Affinity DataEC50:  1.30nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604708(CHEMBL5205546)
Affinity DataEC50:  3.90nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604709(CHEMBL5191700)
Affinity DataEC50:  3.60nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604710(CHEMBL5171955)
Affinity DataEC50:  2nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604711(CHEMBL5191161)
Affinity DataEC50:  1nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604676(CHEMBL5202286)
Affinity DataEC50:  1.20nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604693(CHEMBL5180046)
Affinity DataEC50:  2.20nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604678(CHEMBL5207484)
Affinity DataEC50:  0.900nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604679(CHEMBL5193428)
Affinity DataEC50:  0.400nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604680(CHEMBL5172442)
Affinity DataEC50: >1.00E+3nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604681(CHEMBL5198988)
Affinity DataEC50: >1.00E+3nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604682(CHEMBL5188343)
Affinity DataEC50: >1.00E+3nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM263716(6-(2,4-dichlorophenyl)-5-[4-[(3S)-1-(3-fluoropropy...)
Affinity DataEC50:  1.20nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604683(CHEMBL5185539)
Affinity DataEC50:  1.10nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604684(CHEMBL5174315)
Affinity DataEC50:  0.700nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604686(CHEMBL5197035)
Affinity DataEC50:  1.20nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604687(CHEMBL5177756)
Affinity DataEC50:  1nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604688(CHEMBL5194962)
Affinity DataEC50:  3.90nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604689(CHEMBL5173602)
Affinity DataEC50:  1nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604690(CHEMBL5206306)
Affinity DataEC50:  2.60nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604691(CHEMBL5207013)
Affinity DataEC50:  13nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604692(CHEMBL5198039)
Affinity DataEC50:  2.5nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604694(CHEMBL5190953)
Affinity DataEC50:  1.40nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604685(CHEMBL5179839)
Affinity DataEC50: >1.00E+3nMAssay Description:Induction of ERalpha degradation in human MCF7 cells incubated for 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor beta(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50238741(CHEBI:31638 | Faslodex | Fulvestrant | ICI-182780 ...)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at ERbeta expressed in HEK293/Gal4 cells incubated for 24 hrs in presence of di-arylpropionitrile by luciferase reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604697(CHEMBL5173113)
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at ERalpha expressed in HEK293/Gal4 cells incubated for 24 hrs in presence of estradiol by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604703(CHEMBL5181850)
Affinity DataIC50: 0.600nMAssay Description:Antagonist activity at ERalpha expressed in HEK293/Gal4 cells incubated for 24 hrs in presence of estradiol by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604701(CHEMBL5205039)
Affinity DataIC50: 0.700nMAssay Description:Antagonist activity at ERalpha expressed in HEK293/Gal4 cells incubated for 24 hrs in presence of estradiol by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604706(CHEMBL5171948)
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at ERalpha expressed in HEK293/Gal4 cells incubated for 24 hrs in presence of estradiol by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604705(CHEMBL5205357)
Affinity DataIC50: 0.900nMAssay Description:Antagonist activity at ERalpha expressed in HEK293/Gal4 cells incubated for 24 hrs in presence of estradiol by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604694(CHEMBL5190953)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at ERalpha expressed in HEK293/Gal4 cells incubated for 24 hrs in presence of estradiol by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50238741(CHEBI:31638 | Faslodex | Fulvestrant | ICI-182780 ...)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at ERalpha expressed in HEK293/Gal4 cells incubated for 24 hrs in presence of estradiol by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604707(CHEMBL5169445)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at ERalpha expressed in HEK293/Gal4 cells incubated for 24 hrs in presence of estradiol by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604700(CHEMBL5191391)
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at ERalpha expressed in HEK293/Gal4 cells incubated for 24 hrs in presence of estradiol by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604698(CHEMBL5184413)
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at ERalpha expressed in HEK293/Gal4 cells incubated for 24 hrs in presence of estradiol by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604710(CHEMBL5171955)
Affinity DataIC50: 1.20nMAssay Description:Antagonist activity at ERalpha expressed in HEK293/Gal4 cells incubated for 24 hrs in presence of estradiol by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50604693(CHEMBL5180046)
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at ERalpha expressed in HEK293/Gal4 cells incubated for 24 hrs in presence of estradiol by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
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