Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50017746
TargetGlucagon-like peptide 1 receptor(Rat)
Hospital Regional Universitario

Curated by ChEMBL
LigandPNGBDBM50604669(CHEMBL5208485)
Affinity DataEC50:  0.25nMAssay Description:Positive allosteric modulator activity at GLP-1R in rat INS1 beta-cells assessed potentiation of GLP-1(7-36)NH2 induced insulin secretion incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGlucagon-like peptide 1 receptor(Rat)
Hospital Regional Universitario

Curated by ChEMBL
LigandPNGBDBM50604669(CHEMBL5208485)
Affinity DataEC50:  0.00800nMAssay Description:Positive allosteric modulator activity at GLP-1R in rat INS1 beta-cells assessed potentiation of GLP-1(7-36)NH2 induced insulin secretion incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Hospital Regional Universitario

Curated by ChEMBL
LigandPNGBDBM50604669(CHEMBL5208485)
Affinity DataEC50:  0.100nMAssay Description:Positive allosteric modulator activity at human GLP-1R expressed in HEK293 cells assessed as potentiation of GLP-1(7-36)NH2 induced cAMP accumulation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Hospital Regional Universitario

Curated by ChEMBL
LigandPNGBDBM50604670(CHEMBL5192742)
Affinity DataEC50:  10nMAssay Description:Positive allosteric modulator activity at human GLP-1R expressed in HEK293 cells assessed as activation of calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGlucagon-like peptide 1 receptor(Human)
Hospital Regional Universitario

Curated by ChEMBL
LigandPNGBDBM50604671(CHEMBL5209005)
Affinity DataEC50:  10nMAssay Description:Positive allosteric modulator activity at human GLP-1R expressed in HEK293 cells assessed as activation of calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetGlucagon-like peptide 1 receptor(Rat)
Hospital Regional Universitario

Curated by ChEMBL
LigandPNGBDBM50604669(CHEMBL5208485)
Affinity DataIC50: 6.30nMAssay Description:Positive allosteric modulator activity at GLP-1R in rat INS1 beta-cells assessed potentiation of GLP-1(7-36)NH2 induced insulin secretion at 0.1 nM i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed