Compile Data Set for Download or QSAR
Report error Found 72 Enz. Inhib. hit(s) with all data for entry = 50017739
TargetAtrial natriuretic peptide receptor 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604581(CHEMBL5198683)
Affinity DataKd:  1.63E+6nMAssay Description:Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as dissociation constant by surface plasmon resonance analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Mouse)
University College London

Curated by ChEMBL
LigandPNGBDBM50604566(CHEMBL5193490)
Affinity DataEC50:  3.02E+3nMAssay Description:Agonist activity at NPRC in knock out mouse mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604564(CHEMBL5191531)
Affinity DataKd:  9.57E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as dissociation constant by surface plasmon resonance analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604574(CHEMBL5205961)
Affinity DataKd:  9.90E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as dissociation constant by surface plasmon resonance analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604575(CHEMBL5199911)
Affinity DataKd:  2.57E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as dissociation constant by surface plasmon resonance analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604576(CHEMBL5188425)
Affinity DataKd:  3.69E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as dissociation constant by surface plasmon resonance analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604577(CHEMBL5194742)
Affinity DataKd:  4.51E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as dissociation constant by surface plasmon resonance analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604573(CHEMBL5174834)
Affinity DataKd:  3.08E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as dissociation constant by surface plasmon resonance analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604569(CHEMBL5170051)
Affinity DataKd:  2.20E+5nMAssay Description:Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as dissociation constant by surface plasmon resonance analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604578(CHEMBL5175010)
Affinity DataKd:  8.44E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as dissociation constant by surface plasmon resonance analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604579(CHEMBL5178415)
Affinity DataKd:  2.50E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as dissociation constant by surface plasmon resonance analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604580(CHEMBL5178801)
Affinity DataKd:  1.44E+6nMAssay Description:Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as dissociation constant by surface plasmon resonance analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50604565(CHEMBL5180826)
Affinity DataEC50:  8.64E+3nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation preincubated with M372049 for 15 mins followed by compound treat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604582(CHEMBL5207048)
Affinity DataKd:  4.22E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as dissociation constant by surface plasmon resonance analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604583(CHEMBL5174129)
Affinity DataKd:  7.90E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as dissociation constant by surface plasmon resonance analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604584(CHEMBL5177719)
Affinity DataKd:  8.32E+5nMAssay Description:Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as dissociation constant by surface plasmon resonance analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604565(CHEMBL5180826)
Affinity DataKd:  1.46E+5nMAssay Description:Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as dissociation constant by surface plasmon resonance analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604585(CHEMBL5200513)
Affinity DataKd:  2.01E+5nMAssay Description:Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as dissociation constant by surface plasmon resonance analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604567(CHEMBL5171798)
Affinity DataKd:  2.80E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as dissociation constant by surface plasmon resonance analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604566(CHEMBL5193490)
Affinity DataKd:  3.13E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as dissociation constant by surface plasmon resonance analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604571(CHEMBL5174523)
Affinity DataKd:  2.37E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as dissociation constant by surface plasmon resonance analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604586(CHEMBL5191995)
Affinity DataKd:  2.96E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as dissociation constant by surface plasmon resonance analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604572(CHEMBL5208520)
Affinity DataKd:  2.38E+4nMAssay Description:Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as dissociation constant by surface plasmon resonance analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604568(CHEMBL5175209)
Affinity DataKd:  3.81E+5nMAssay Description:Binding affinity to CM5 sensor chip immobilized human NPR-C (27 to 541 residues) assessed as dissociation constant by surface plasmon resonance analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50604564(CHEMBL5191531)
Affinity DataEC50:  1.43E+3nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Mouse)
University College London

Curated by ChEMBL
LigandPNGBDBM50604564(CHEMBL5191531)
Affinity DataEC50:  2.64E+3nMAssay Description:Agonist activity at NPRC in knock out mouse mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Mouse)
University College London

Curated by ChEMBL
LigandPNGBDBM50604566(CHEMBL5193490)
Affinity DataEC50:  2.51E+3nMAssay Description:Agonist activity at NPRC in wild type mouse mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Mouse)
University College London

Curated by ChEMBL
LigandPNGBDBM50604565(CHEMBL5180826)
Affinity DataEC50:  1.58E+3nMAssay Description:Agonist activity at NPRC in wild type mouse mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Mouse)
University College London

Curated by ChEMBL
LigandPNGBDBM50604564(CHEMBL5191531)
Affinity DataEC50:  1.16E+3nMAssay Description:Agonist activity at NPRC in wild type mouse mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50604572(CHEMBL5208520)
Affinity DataEC50:  3.76E+3nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50604571(CHEMBL5174523)
Affinity DataEC50:  4.43E+3nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50604566(CHEMBL5193490)
Affinity DataEC50:  1.02E+5nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50604567(CHEMBL5171798)
Affinity DataEC50:  6.24E+3nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50604570(CHEMBL5197280)
Affinity DataEC50:  7.81E+4nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50604565(CHEMBL5180826)
Affinity DataEC50:  1.55E+4nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50604569(CHEMBL5170051)
Affinity DataEC50:  6.20E+3nMAssay Description:Agonist activity at NPRC in rat aorta assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50604566(CHEMBL5193490)
Affinity DataEC50:  390nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50604570(CHEMBL5197280)
Affinity DataEC50:  3.45E+3nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50604565(CHEMBL5180826)
Affinity DataEC50:  860nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50604569(CHEMBL5170051)
Affinity DataEC50:  2.22E+4nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50604564(CHEMBL5191531)
Affinity DataEC50:  970nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604568(CHEMBL5175209)
Affinity DataEC50:  6.00E+4nMAssay Description:Displacement of Flu-P19 probe from human NPR-C (27 to 541 residues) by fluorescence polarization analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604567(CHEMBL5171798)
Affinity DataEC50:  3.27E+5nMAssay Description:Displacement of Flu-P19 probe from human NPR-C (27 to 541 residues) by fluorescence polarization analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604566(CHEMBL5193490)
Affinity DataEC50:  3.20E+4nMAssay Description:Displacement of Flu-P19 probe from human NPR-C (27 to 541 residues) by fluorescence polarization analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50604566(CHEMBL5193490)
Affinity DataEC50:  360nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation preincubated with M372049 for 15 mins followed by compound treat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Rat)
University College London

Curated by ChEMBL
LigandPNGBDBM50604564(CHEMBL5191531)
Affinity DataEC50:  470nMAssay Description:Agonist activity at NPRC in rat small mesenteric arteries assessed as vasorelaxation preincubated with M372049 for 15 mins followed by compound treat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAtrial natriuretic peptide receptor 3(Mouse)
University College London

Curated by ChEMBL
LigandPNGBDBM50604565(CHEMBL5180826)
Affinity DataEC50:  1.01E+4nMAssay Description:Agonist activity at NPRC in knock out mouse mesenteric arteries assessed as vasorelaxation by Organ bath assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCytochrome P450 2C9(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604564(CHEMBL5191531)
Affinity DataIC50: 4.96E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate preincubated for 10 mins followed by NADPH addition and measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCytochrome P450 2C8(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604573(CHEMBL5174834)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using amodiaquine as a substrate preincubated for 10 mins followed by NADPH addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetCytochrome P450 2C8(Human)
University College London

Curated by ChEMBL
LigandPNGBDBM50604566(CHEMBL5193490)
Affinity DataIC50: 7.72E+3nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using amodiaquine as a substrate preincubated for 10 mins followed by NADPH addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Displayed 1 to 50 (of 72 total ) | Next | Last >>
Jump to: