Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50015890
TargetMu-type opioid receptor(Human)
Allegheny General Hospital

Curated by ChEMBL
LigandPNGBDBM50590365(CHEMBL5197033)
Affinity DataIC50: 5.10nMAssay Description:Antagonist activity at human MOR expressed in CHO-K1 cells assessed as reduction in fentanyl induced cAMP production incubated for 30 mins by Lance u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Allegheny General Hospital

Curated by ChEMBL
LigandPNGBDBM50590364(CHEMBL5180599)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human MOR expressed in CHO-K1 cells assessed as reduction in fentanyl induced cAMP production incubated for 30 mins by Lance u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Allegheny General Hospital

Curated by ChEMBL
LigandPNGBDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataIC50: 27nMAssay Description:Antagonist activity at human MOR expressed in CHO-K1 cells assessed as reduction in fentanyl induced cAMP production incubated for 30 mins by Lance u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMedPDB3D3D Structure (crystal)