Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50015394
TargetCapsid protein(HBV)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586191(CHEMBL5079279)
Affinity DataEC50:  2.79E+3nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586214(CHEMBL5089577)
Affinity DataEC50:  50nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586213(CHEMBL5094309)
Affinity DataEC50:  42nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586212(CHEMBL5094846)
Affinity DataEC50:  60nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586211(CHEMBL5077990)
Affinity DataEC50:  195nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586210(CHEMBL5091917)
Affinity DataEC50:  26nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586209(CHEMBL5081966)
Affinity DataEC50:  15nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586208(CHEMBL5077879)
Affinity DataEC50:  182nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586207(CHEMBL5086392)
Affinity DataEC50:  83nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586206(CHEMBL5082289)
Affinity DataEC50:  432nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586205(CHEMBL5089980)
Affinity DataEC50:  54nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586204(CHEMBL5080219)
Affinity DataEC50:  922nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586203(CHEMBL5078826)
Affinity DataEC50:  4.08E+3nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586201(CHEMBL5069699)
Affinity DataEC50:  735nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586190(CHEMBL5084734)
Affinity DataEC50: >1.00E+4nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586192(CHEMBL5082630)
Affinity DataEC50: >1.00E+4nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586193(CHEMBL5084299)
Affinity DataEC50: >1.00E+4nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586194(CHEMBL5077232)
Affinity DataEC50: >1.00E+4nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586195(CHEMBL5094660)
Affinity DataEC50: >1.00E+4nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586196(CHEMBL5073410)
Affinity DataEC50: >1.00E+4nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586197(CHEMBL5086863)
Affinity DataEC50:  511nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586198(CHEMBL5090461)
Affinity DataEC50:  818nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586199(CHEMBL5084819)
Affinity DataEC50:  852nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586200(CHEMBL5089316)
Affinity DataEC50:  947nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCapsid protein(HBV)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586202(CHEMBL5075853)
Affinity DataEC50:  456nMAssay Description:Modulation of capsid assembly in HBV infected in human HepG2.2.15 cells assessed as inhibition of viral DNA replication preincubated for 3 days follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586210(CHEMBL5091917)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human CYP1A2 by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586210(CHEMBL5091917)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human CYP2C9 by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586210(CHEMBL5091917)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human CYP2D6 by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586210(CHEMBL5091917)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human CYP3A4 using midazolam as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586210(CHEMBL5091917)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human CYP2C19 by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586210(CHEMBL5091917)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Shanghai Hengrui Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50586210(CHEMBL5091917)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human CYP3A4 using testosterone as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed