Compile Data Set for Download or QSAR
Report error Found 78 Enz. Inhib. hit(s) with all data for entry = 50017702
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604214(CHEMBL5170189)
Affinity DataIC50: 250nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604227(CHEMBL5182403)
Affinity DataIC50: 290nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604210(CHEMBL5174303)
Affinity DataIC50: 360nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604201(CHEMBL5203054)
Affinity DataIC50: 360nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604212(CHEMBL5190252)
Affinity DataIC50: 380nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604209(CHEMBL5169392)
Affinity DataIC50: 390nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604204(CHEMBL5188949)
Affinity DataIC50: 410nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604204(CHEMBL5188949)
Affinity DataIC50: 420nMAssay Description:Antagonist activity at 5-HT2B receptor (unknown origin) transfected in HEK293 cells assessed as beta-arrestin translocation by Tango assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604208(CHEMBL5202029)
Affinity DataIC50: 420nMAssay Description:Antagonist activity at 5-HT2B receptor (unknown origin) transfected in HEK293 cells assessed as beta-arrestin translocation by Tango assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604227(CHEMBL5182403)
Affinity DataIC50: 420nMAssay Description:Antagonist activity at 5-HT2B receptor (unknown origin) transfected in HEK293 cells assessed as beta-arrestin translocation by Tango assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604193(CHEMBL5187824)
Affinity DataIC50: 420nMAssay Description:Antagonist activity at 5-HT2B receptor (unknown origin) transfected in HEK293 cells assessed as beta-arrestin translocation by Tango assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604208(CHEMBL5202029)
Affinity DataIC50: 440nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604200(CHEMBL5205425)
Affinity DataIC50: 470nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604228(CHEMBL5178349)
Affinity DataIC50: 520nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604226(CHEMBL5172009)
Affinity DataIC50: 540nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604225(CHEMBL5201467)
Affinity DataIC50: 570nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604214(CHEMBL5170189)
Affinity DataIC50: 570nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604202(CHEMBL5199983)
Affinity DataIC50: 610nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604218(CHEMBL5197311)
Affinity DataIC50: 630nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604205(CHEMBL5178255)
Affinity DataIC50: 670nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604206(CHEMBL5197376)
Affinity DataIC50: 680nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604215(CHEMBL5195432)
Affinity DataIC50: 700nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604227(CHEMBL5182403)
Affinity DataIC50: 710nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604215(CHEMBL5195432)
Affinity DataIC50: 770nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604199(CHEMBL5178772)
Affinity DataIC50: 780nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604199(CHEMBL5178772)
Affinity DataIC50: 790nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604211(CHEMBL5186344)
Affinity DataIC50: 810nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604212(CHEMBL5190252)
Affinity DataIC50: 880nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604217(CHEMBL5171368)
Affinity DataIC50: 900nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604219(CHEMBL5176376)
Affinity DataIC50: 900nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604213(CHEMBL2098167 | TCMDC-142373 | GSK1783663A)
Affinity DataIC50: 970nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604222(CHEMBL5187427)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604200(CHEMBL5205425)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604213(CHEMBL2098167 | TCMDC-142373 | GSK1783663A)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604197(CHEMBL5180340)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604218(CHEMBL5197311)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604206(CHEMBL5197376)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604193(CHEMBL5187824)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604198(CHEMBL5186455)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604216(CHEMBL5176001)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604198(CHEMBL5186455)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604228(CHEMBL5178349)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604193(CHEMBL5187824)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604211(CHEMBL5186344)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604202(CHEMBL5199983)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604203(CHEMBL5203795)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604222(CHEMBL5187427)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604201(CHEMBL5203054)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604210(CHEMBL5174303)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50604204(CHEMBL5188949)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
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