Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50017153
TargetFKBP12A/mTOR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50600034(CHEMBL5194372)
Affinity DataIC50: 125nMAssay Description:Inhibition of human full length recombinant mTOR/FKBP12 in presence of [gamma-33P]ATP incubated for 40 mins by radiometric scintillation counting ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50600034(CHEMBL5194372)
Affinity DataIC50: 136nMAssay Description:Inhibition of human full length recombinant mTOR in presence of [gamma-33P]ATP incubated for 40 mins by radiometric scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandPNGBDBM50600034(CHEMBL5194372)
Affinity DataIC50: 2.15E+3nMAssay Description:Inhibition of recombinant human full length PI3K p110delta/p85a using phosphatidylinositol-4, 5-bisphosphate as substrate incubated for 40 mins in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandPNGBDBM50600034(CHEMBL5194372)
Affinity DataIC50: 2.72E+3nMAssay Description:Inhibition of human PI3K-C2alpha (299 to ens residues) using phosphatidylinositol-4, 5-bisphosphate as substrate incubated for 40 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50600034(CHEMBL5194372)
Affinity DataIC50: 9.44E+3nMAssay Description:Inhibition of human recombinant B-Raf (416 to end residues) using myelin basic protein as substrate in presence of [gamma-33P]ATP incubated for 40 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed